Epidemiologic and clinical characteristics of COVID-19 patients admitted in a tertiary care hospital in Khulna city

Authors

  • Syed Didarul Haque Assistant Professor, Department of Pharmacology & Therapeutics, Gazi Medical College, Khulna, Bangladesh
  • Muhammad Ashraful Kabir Associate Professor, Department of Respiratory Medicine, Gazi Medical College & Hospital, Khulna, Bangladesh
  • Prithwy Shankar Biswas Assistant Professor, Department of Biochemistry, Gazi Medical College, Khulna, Bangladesh
  • Abu Md Mayeenuddin Al Amin Assistant Professor, Department of Microbiology, Gazi Medical College, Khulna, Bangladesh
  • Md Barkot Ali Associate Professor & Head, Department of Paediatrics, Gazi Medical College & Hospital, Khulna, Bangladesh
  • Baishakhi Islam Associate Professor & Head Department of Pharmacology & Therapeutics, Gazi Medical College, Khulna, Bangladesh

DOI:

https://doi.org/10.3329/mediscope.v9i1.58521

Keywords:

COVID-19, coronavirus

Abstract

Background & objective: The outbreak of coronavirus disease 2019 (COVID-19) has become a large threat to global health due to its high contagious nature and varied mortality. The number of infected cases and deaths are rising exponentially all over the world, including Bangladesh. This study aims to investigate the epidemiological and clinical features of COVID-19 patients admitted in Gazi Medical College Hospital (GMCH), Khulna, Bangladesh.

Methods: In this study, we included 110 RT-PCR positive COVID-19 cases at GMCH, Khulna, Bangladesh from 1 July, 2021 to 31 August, 2021. Demographic, clinical, laboratory and radiological data of the patients were recorded and analyzed.

Results: Among 110 study subjects, 51.8% were male. The mean age was 52.6 years, with majority (43.6%) belonging to the age group of 40-59 years. Upon admission, the most frequent symptoms were fever (94.5%), cough (86.4%) and dyspnea (79.1%). Diabetes mellitus (42.7%) and hypertension (33.6%) were the most common comorbidities. Regarding laboratory parameters, neutrophilia and lymphocytopenia were observed in 72.7% and 58.2% cases, respectively. The mean D-dimer (2.9 mg/l) and CRP (61.7 mg/l) levels were above their normal limits. In high resolution CT scan of the chest (HRCT chest), bilateral lung involvement was present in 85.5% cases. Ground-glass appearance was the most frequent (89.1%) radiologic pattern. Among the study subjects, empirical antibiotic, antiviral (remdesivir) drug, and systemic glucocorticoid were given to 97.3%, 83.6% and 56.4% patients, respectively. Total 15 (13.6%) patients were severely affected with COVID-19 and admitted to the ICU, requiring mechanical ventilation. During our study, 12 patients (10.9%) died either due to multiple organ dysfunction syndrome or cardio-respiratory failure.

Conclusion: The study provides key information about clinical characteristics and general management of COVID-19 patients, which may help physicians to identify the factors associated with adverse outcomes in this disease.

Mediscope 2022;9(1): 9-15

Downloads

Download data is not yet available.
Abstract
30
PDF
41

Downloads

Published

2022-04-19

How to Cite

Haque, S. D. ., Kabir, M. A. ., Biswas, P. S. ., Al Amin, A. M. M. ., Ali, M. B. ., & Islam, B. . (2022). Epidemiologic and clinical characteristics of COVID-19 patients admitted in a tertiary care hospital in Khulna city. Mediscope, 9(1), 9–15. https://doi.org/10.3329/mediscope.v9i1.58521

Issue

Vol. 9 No. 1 (2022)

Section

Original Articles

License

Copyright (c) 2022 SD Haque, MA Kabir, PS Biswas, AMM Al Amin, MB Ali, B Islam

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish in the Mediscope agree to the following terms that:

  1. Authors retain copyright and grant Mediscope the right of first publication of the work.

  2. Creative Commons Licence
    Articles in Mediscope are licensed under a Creative Commons Attribution 4.0 International License CC BY-4.0. This license permits use, distribution and reproduction in any medium, provided the original work is properly cited.
  1. Authors are able to enter into separate, additional contractual arrangements for the distribution of the journal’s published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  2. Authors are permitted to post their work online (e.g., in institutional repositories or on their website) as it can lead to productive exchanges, as well as greater citation of published work.