Current Trend of Prescribing Anticoagulant and Antiviral Drugs in the Treatment of COVID- 19 Patients in a Corona Dedicated Hospital in Khulna

Authors

  • Muhammad Ashraful Kabir Associate Professor, Department of Respiratory Medicine, Gazi Medical College & Hospital, Khulna, Bangladesh.
  • Baishakhi Islam Associate Professor & Head, Department of Pharmacology & Therapeutics, Gazi Medical College, Khulna, Bangladesh.
  • Tasnim Rahman Associate Professor, Department of Pathology, Gazi Medical College, Khulna, Bangladesh.
  • Tamanna Jannat Assistant Professor, Department of Pharmacology & Therapeutics, Bikrampur Bhuiyan Medical College, Munshiganj, Bangladesh.
  • Jesmin Zahan Tuli Associate Professor (c.c), Department of Biochemistry, Sheikh Hasina Medical College, Jamalpur, Bangladesh.
  • Abdullah Al Faroque Associate Professor & Head, Department of Pathology, Gazi Medical College, Khulna, Bangladesh.

DOI:

https://doi.org/10.3329/mediscope.v10i1.65402

Keywords:

Enoxaparin, Remdesivir, COVID-19

Abstract

Background: Thrombo-embolic incidence secondary to COVID-19 with increased mortality rate has become a global concern. Anticoagulants are widely used to prevent mortality. On the other hand, antiviral therapy has a potential effect against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

Aims & objectives: This study aims to assess the use pattern of anticoagulant and antiviral drugs against COVID-19.

Methods: This is an observational cross-sectional study where two hundred COVID-19-positive patients of both sexes and different age groups who received anticoagulants and antivirals were recruited. All data were compiled in a Microsoft excel spreadsheet. Results were expressed in frequency & percentage.

Results: Out of 200 patients, there were 115 males (57.5%) & 85 females (42.5%); the majority (56%) belonged to the age group between 30 to 60 years. Clinically, patients were categorized into mild (25%), moderate (32%), severe (37.5%), and critical (5.5%) cases. In this study, 88% of patients received low molecular weight heparin (enoxaparin) in a prophylactic dose and 12% of patients received in a therapeutic dose. Among the antivirals, remdesivir (84%) followed by favipiravir (16%) were the most commonly prescribed drugs.

Conclusion: Anticoagulant (enoxaparin) and antiviral (remdesivir) drugs are frequently prescribed in the treatment of COVID-19 patients.

Mediscope 2023;10(1):10-16

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Published

2023-04-11

How to Cite

Kabir, M. A. ., Islam, B. ., Rahman, T. ., Jannat, T. ., Tuli, J. Z. ., & Faroque, A. A. . (2023). Current Trend of Prescribing Anticoagulant and Antiviral Drugs in the Treatment of COVID- 19 Patients in a Corona Dedicated Hospital in Khulna. Mediscope, 10(1), 10–16. https://doi.org/10.3329/mediscope.v10i1.65402

Issue

Vol. 10 No. 1 (2023)

Section

Original Articles

License

Copyright (c) 2023 Muhammad Ashraful Kabir, Baishakhi Islam, Tasnim Rahman, Tamanna Jannat, Jesmin Zahan Tuli, Abdullah Al Faroque

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