Evaluation of Palpable Breast Lesions by Fine Needle Aspiration Cytology in A Tertiary Medical College Hospital

Authors

  • Syeda Noorjahan Karim Associate Professor, Department of Pathology, Gazi Medical College, Khulna, Bangladesh.
  • Purabi Sarker Assistant Professor and Head, Department of Pathology, Ad-din Akij Medical College, Khulna, Bangladesh.
  • Israt Jahan Zeba Assistant Professor, Department of Surgery, Gazi Medical College Hospital, Khulna, Bangladesh.
  • Md Moshiur Rahman Assistant Professor, Department of Anatomy, Ad-din Akij Medical College, Khulna, Bangladesh.
  • Rezwana Karim Assistant Professor, Department of Pathology, US-Bangla Medical College, Narayanganj, Bangladesh.
  • Amina Jannat Peea Associate Professor & Head, Department of Gynaecology & Obstetrics, Gazi Medical College, Khulna, Bangladesh.
  • Banga Kamal Basu Ex-Professor and Head, Department of Surgery, Gazi Medical College Hospital, Khulna, Bangladesh.

DOI:

https://doi.org/10.3329/mediscope.v12i1.79894

Keywords:

FNAC, Palpable breast lesion, Cytology, Fibroadenoma, Ductal carcinoma

Abstract

Background: Breast lesions are heterogeneous diseases that consist of several distinct entities with remarkably different characteristic features. Presence of lump in the breast causes anxiety, and apprehension in every woman. This may be attributed to the increasing public awareness of breast cancer.

Aim: The study aimed to observe and analyze the diverse cytomorphological features of palpable breast lump by using fine needle aspiration cytology (FNAC).

Methods: This cross-sectional study was carried out at the Department of Pathology, Gazi Medical College, Khulna; from October 2021 to September 2022. In this study, fifty-eight (58) samples of breast lumps were collected by fine needle aspiration cytology, processed and stained with hematoxylin and eosin. After staining, all the slides were thoroughly examined under light microscope stains to confirm the diagnosis as well as to evaluate cytopathologic characteristics.  The data were tabulated and statistical analysis was performed.

Results: Out of 58 cases, 44 (75.9%) samples belonged to age 21-50 years and the mean age was 34.22±12.09 years. The right breast (53.4%) was found affected more than the left breast and most of the lesions were in the upper and outer quadrants (51.7%). Cytologically, the most common lesion was fibroadenoma (29.3%), followed by fibrocystic change and ductal carcinoma (13.8%). A strong positive correlation (r = 0.510, p = 0.000) was found between the age and the cytological characteristics. A significant (p = 0.039) but weakly positive correlation (r = 0.277) was found between the tumor size and the cytological study. No significant correlation was found between the consistency, quadrant, mobility and the cytological characteristics of the tumor.

Conclusion: FNAC is a simple, safe, reproducible and minimally invasive diagnostic test. It is not a substitute for open biopsy, rather with careful clinical assessment, it should be used to complement histopathology in different clinical settings.

Mediscope 2025;12(1): 34-38

Downloads

Abstract
41
PDF
42

Downloads

Published

2025-03-17

How to Cite

Karim, S. N., Sarker, P., Zeba, I. J., Rahman, M. M., Karim, R., Peea, A. J., & Basu, B. K. (2025). Evaluation of Palpable Breast Lesions by Fine Needle Aspiration Cytology in A Tertiary Medical College Hospital. Mediscope, 12(1), 34–38. https://doi.org/10.3329/mediscope.v12i1.79894

Issue

Vol. 12 No. 1 (2025)

Section

Original Articles

License

Copyright (c) 2025 Syeda Noorjahan Karim, Purabi Sarker, Israt Jahan Zeba, Md. Moshiur Rahman, Rezwana Karim, Amina Jannat Peea, Banga Kamal Basu

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish in the Mediscope agree to the following terms that:

  1. Authors retain copyright and grant Mediscope the right of first publication of the work.

  2. Creative Commons Licence
    Articles in Mediscope are licensed under a Creative Commons Attribution 4.0 International License CC BY-4.0. This license permits use, distribution and reproduction in any medium, provided the original work is properly cited.
  1. Authors are able to enter into separate, additional contractual arrangements for the distribution of the journal’s published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  2. Authors are permitted to post their work online (e.g., in institutional repositories or on their website) as it can lead to productive exchanges, as well as greater citation of published work.