Impact of Diabetic Mellitus on the Effect of Streptokinase in Acute Myocardial Infarction Patients

Authors

  • Md Faruque Uddin Clinical & interventional Cardiologist Associate Professor & Head of the Department of Cardiology, North East Medical College, Sylhet
  • AK Fazlul Hoque Clinical & interventional Cardiologist Associate Professor, Cardiology North East Medical College, Sylhet

DOI:

https://doi.org/10.3329/medtoday.v24i1.14108

Keywords:

Diabetic Mellitus, Streptokinase, Myocardial Infarction

Abstract

A prospective interventional study was carried out to compare  the thrombolytic effect of streptokinase between diabetic and  non-diabetic myocardial infarction patients. Out of 187 study  subjects with acute ST segment elevation myocardial  infarction (STEMI), admitted at coronary care unit, 126  patients were non-diabetic and 61 patients were diabetic.  Streptokinase was administered to all patients. Resolution  (reduction) of elevated ST segment was evaluated after 90 min  of streptokinase administration. Successful reperfusion  (=70% ST-resolution) was significantly higher in  non-diabetic than diabetic (p<0.001), while failed reperfusion  (<30% ST resolution) was significantly higher in diabetic  patients (p<0.001). It may be concluded that diabetes mellitus  might affect the thrombolytic outcome of acute myocardial  infarction patients with diabetes mellitus.

DOI: http://dx.doi.org/10.3329/medtoday.v24i1.14108

Medicine TODAY Vol.24(1) 2012 pp.16-19

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Published

2013-03-09

How to Cite

Uddin, M. F., & Hoque, A. F. (2013). Impact of Diabetic Mellitus on the Effect of Streptokinase in Acute Myocardial Infarction Patients. Medicine Today, 24(1), 16–19. https://doi.org/10.3329/medtoday.v24i1.14108

Issue

Vol. 24 No. 1 (2012)

Section

Original Articles