Time of Apyrexia after Azithromycin Therapy in Uncomplicated Childhood Typhoid Fever

Authors

  • Kartick Chanda Shaha Associate Professor (c.c), Department of Pharmacology, Dhaka National Medical College, Dhaka, Bangladesh.
  • Hasan Moshiur Shawon Junior Consultant, Department of Pediatrics, District Hospital, Pirojpur, Bangladesh.
  • Ahsanul Haque Research Assistant, Department of Microbiology, Gono Bishwabidyalay Savar, Dhaka, Bangladesh.
  • Sadnan Taher Executive, Square Pharmaceuticals PLC, Gazipur, Dhaka, Bangladesh.
  • S M Ashik Faysal Manager, Lab Operation and Business Development, AI Khan Lab Limited, Dhaka, Bangladesh.

DOI:

https://doi.org/10.3329/medtoday.v37i2.83204

Keywords:

Azithromycin, Uncomplicated Typhoid Fever, Salmonella typhi/paratyphi.

Abstract

Introduction with Objective: The aim of the present study was to assess the time of apyrexia after Azithromycin therapy in uncomplicated childhood Typhoid Fever. Materials and Methods: A cross sectional study was conducted in the Department of pediatrics, Dhaka National Medical College, Dhaka from July 2024 to October 2024. According to selection criteria one hundred subjects were selected with the age ranging from 1-12 years of either sex who was diagnosed as typhoid fever. Widal test positive was included for the study & specific antibiotic Azithromycin was started. Statistical analyses of the results were obtained by using window based computer software devised with Statistical Packages for Social Sciences (SPSS-20.1). Results: Most of the patients (n=51) belong to 6-8 years age group. Young male patients (52%) were more than the young female patients (48%). Majority of the patients (n=39) time of apyrexia after taking antibiotic was 4 days. Almost three fourth patients (75.0%) had nausea after taking antibiotic. Conclusion: Azithromycin is effective in the treatment of childhood typhoid fever. Majority of the patient’s time of apyrexia after taking antibiotic was 4 days.

Medicine Today 2025, Vol.37 (2): 241-243

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Published

2025-07-30

How to Cite

Chanda Shaha, K., Moshiur Shawon, H., Haque, A., Taher, S., & Faysal, S. M. A. (2025). Time of Apyrexia after Azithromycin Therapy in Uncomplicated Childhood Typhoid Fever. Medicine Today, 37(2), 241–243. https://doi.org/10.3329/medtoday.v37i2.83204

Issue

Vol. 37 No. 2 (2025)

Section

Original Articles