Immunogenicity of BAU-Bivalent Salmonella and Fowl Cholera Vaccines in Shuvra Chickens

Abstract

The study was performed to investigate the immunogenicity of Salmonella and Fowl cholera vaccine prepared at BAU using Shuvra strain of chickens administered with BAU Salmonella bivalent and BAU Fowl cholera vaccines prepared by Livestock and Poultry Vaccine Research and Production Centre, (LPVRPC). A total of 60 apparently healthy BLRI strains Shuvra were used in this study. The birds were divided into three groups, consisting of 20 birds in each group. Shuvra- A group birds were vaccinated with BAU Salmonella bivalent vaccine, Shuvra-B group birds with BAU Fowl cholera vaccines and Shuvra-C group birds were used as unvaccinated control. The birds, except the ones in group C, were vaccinated intramuscularly (0.5ml) at 8 weeks of age followed by a booster dose at 12 weeks of age. Sera samples were collected on day 56, 85, 105 days and after challenge at 140 days age of birds. Secondary (booster) vaccination (P< 0.05) exhibited a significant level of antibody response. The antibody titre of these birds slowly descended till four weeks of challenge test. It was observed that a dependable level of immunogenicity of BAU Salmonella Bivalent and BAU Fowl cholera vaccine was observed when administered under this schedule followed in Shuvra strain of chickens.

DOI: http://dx.doi.org/10.3329/mh.v1i2.14089

Microbes and Health, 2012 1(2): 50-53