Antibody level against COVID-19 among the vaccinated infected and non-infected doctors by SARS-COV-2: A Comparative study

Authors

  • Nazma Akhter Asst. Prof. of Biochemistry, East-West Medical College, Dhaka, Bangladesh https://orcid.org/0000-0003-0826-4310
  • Forhadul Hoque Mollah Prof. of Biochemistry, BSMMU (Bangabandhu Sheikh Mujib Medical University), Bangladesh
  • Nowrose Jahan Prof. of Biochemistry, Sir Salimullah Medical College. Dhaka, Bangladesh
  • Jurdi Adam Assistant professor of Psychiatry, President Abdul Hamid Medical College. Dhaka, Bangladesh
  • Md Arif Hossain MD resident Oncology Department, BSMMU, Bangladesh
  • Md Zaforullah Chowdhury Prof. of Microbiology, East-West Medical College, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/updcj.v12i2.59770

Keywords:

COVID-19, Vaccination, infected and Non-infected Doctors, SARS-COV--2

Abstract

Introduction: A novel coronavirus (2019-nCoV or SARS-CoV-2) emerged at the end of 2019 in Wuhan, Hubei province, China named as COVID-19. IgM, the first antibody produced by the body, is generated gradually 1 week after symptom onset and declines by 4 weeks after the COVID infection. In this background, the antibody response was observed in vaccinated (by Oxford-AstraZeneca) doctors of SSMC(Sir Salimullah Medical College) with or without previous COVID-19 infection. Methodology: This cross-sectional analytical study was conducted in the Department of Biochemistry and Molecular Biology at SSMC and BSMMU. A total of 70 doctors of SSMC aged 25-59 years were enrolled according to inclusion criteria. Among them 35 vaccinated doctors were previously infected by SARS-CoV-2 regarded as group A and another vaccinated 35 doctors were non-infected regarded as group B. Collected data was analyzed by Statistical Package for Social Science 26 (SPSS 26). The data were expressed as frequency and percentage, mean ± SD for normally distributed data or median (inter-quartile rage) for data not normally distributed. Mann-Whitney test was done to compare IgG status between vaccinated SARS-CoV-2 infected and non-infected individuals. Result: There was significantly higher level of antibodies (serum IgG level) present in fully vaccinated doctors with previous SARS-CoV-2 infection than in only vaccinated doctors without prior infection.

Update Dent. Coll. j: 2022; 12(2): 19-23

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Published

2022-10-10

How to Cite

Akhter, N. ., Mollah, F. H. ., Jahan, N., Adam, J. ., Hossain, M. A., & Chowdhury, M. Z. . (2022). Antibody level against COVID-19 among the vaccinated infected and non-infected doctors by SARS-COV-2: A Comparative study. Update Dental College Journal, 12(2), 19–23. https://doi.org/10.3329/updcj.v12i2.59770

Issue

Vol. 12 No. 2 (2022)

Section

Original Articles

License

Copyright (c) 2022 Nazma Akhter, Forhadul Hoque Mollah, Nowrose Jahan, Jurdi Adam, Md. Arif Hossain, Md. Zaforullah Chowdhury

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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