Polycythaemia Rubra Vera: A Case Report & Review of Literature
DOI:
https://doi.org/10.3329/uhj.v6i2.7259Keywords:
Polycythaemia Rubra Vera(PRV), Thrombosis, Ischemic strokeAbstract
We report a case of 73 year old woman with known risk factor (hypertension) for cerebrovascular disease who developed a TIA like symptom & vertigo with spontaneous clinical improvement. CT showed left cerebral infarct. Haematological test revealed PRV. Clinical improvement was associated with a reduction in haematocrit levels. Hydroxyurea appears to be the least leukemogenic myelosuppressive agent in long term prospective clinical PRV studies extending observation period of >10 years. Low dose aspirin will prevent the microvascular thrombotic complications of thrombocythaemia associated with PRV in remission after phlebotomy.
Key words: Polycythaemia Rubra Vera(PRV); Thrombosis; Ischemic stroke
DOI: 10.3329/uhj.v6i2.7259
University Heart Journal Vol. 6, No. 2, July 2010 pp.114-116
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