In-vitro cytotoxicity and antioxidant property evaluation from methanolic extract of Cuscuta Reflexa flowers

Authors

  • Md Hossan Sakib Department of Pharmacy, University of Science and Technology Chittagong, Chittagong
  • Mohammad Shahadat Hossain Department of Pharmacy, University of Science and Technology Chittagong, Chittagong
  • Muhammad Sazzad Hossain Department of Pharmacy, University of Science and Technology Chittagong, Chittagong
  • Asif Al Mahmood Department of Pharmacy, University of Science and Technology Chittagong, Chittagong
  • Md Yasin Sarkar Department of Pharmacy, International Islamic University Chittagong, Chittagong
  • Sadequr Rahman Department of Pharmacy, International Islamic University Chittagong, Chittagong
  • Limon Kanti Shill Department of Pharmacy, International Islamic University Chittagong, Chittagong

DOI:

https://doi.org/10.3329/ajmbr.v1i2.25623

Keywords:

Cuscuta reflexa, cytotoxicity, scavenging, reducing power, anti-oxidant

Abstract

This investigation is made upon the plant Cuscuta reflexa, the flowers of it, to find out its Cytotoxicity property. The anti-oxidant property of this plant part was investigated using methanol extraction. Methanolic extract of Cuscuta reflexa.Was used to evaluate its cytotoxicity in Brine shrimp lethality bioassay where vincristine sulphate was used as standard drug. In Brine shrimp lethality bioassay, LC50 value of the extract was 36.72?g/ml and vincristine sulphate served as the positive control showed LC50 value 10.51?g/ml. So, compared to vincristine sulphate, it is evident that the methanol extract of flowers of Cuscuta reflexa was cytotoxic. In case of anti-oxidant the scavenging power (IC50) of DPPH radical was 29.26, 17.07, 18.29, 19.55 and 54.87?g/ml respectively.

Asian J. Med. Biol. Res. June 2015, 1(2): 285-291


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Author Biography

Md Hossan Sakib, Department of Pharmacy, University of Science and Technology Chittagong, Chittagong



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Published

2015-11-23

How to Cite

Sakib, M. H., Hossain, M. S., Hossain, M. S., Mahmood, A. A., Sarkar, M. Y., Rahman, S., & Shill, L. K. (2015). In-vitro cytotoxicity and antioxidant property evaluation from methanolic extract of Cuscuta Reflexa flowers. Asian Journal of Medical and Biological Research, 1(2), 285–291. https://doi.org/10.3329/ajmbr.v1i2.25623

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