Establishment of reference ranges for Serum Leptin and C-Peptide using enzymelinked immmunosorbent assay method: a preliminary report

Authors

  • Mainasara Abdullah Sulaiman Department of Chemical Pathology & Immunology, College of Health Sciences, UDU
  • Dahiru Shafi’u Gumel Department of Chemical Pathology & Immunology, College of Health Sciences, UDU
  • Umar Zayyanu Usman Department of Physiology, College of Health Sciences, UDU
  • Anaja Peter Ocheni Department of Chemical Pathology, Faculty of Medicine, Ahmadu Bello University
  • Yakubu Abdulmumini Department of Medicine, Faculty of Clinical Sciences, College of Health Sciences, UDU
  • Rosemary Nwaelugo Adanze Department of Chemical Pathology, Ahmadu Bello University Teaching Hospital
  • Yeldu Mohammed Haruna Department of Chemical Pathology, Faculty of Medical Laboratory Sciences, Usmanu Danfadioyo University

DOI:

https://doi.org/10.3329/ajmbr.v2i3.30122

Keywords:

reference ranges, Leptin, C-Peptide, ELISA, Dutse, Nigeria

Abstract

Reference ranges (RR) or Reference Intervals (RIs) are very important values for accurate interpretation of clinical laboratory test results. Any test result that is not accompanied by a valid RR value is less informative and may not be interpreted correctly. However, reference values of most analytes for Nigerian population are not readily available. The present study aims at establishing reference values of Serum Leptin and C-Peptide for Dutse, Jigawa State. In a cross sectional study, eighty (80) reference individuals were recruited. Serum Leptin and C-Peptide were analysed using ELISA methods. Following an accepted guideline, population specific reference intervals were established for these analytes and found to be 3.13ng/mL to 14.09ng/mL for Leptin and 0.56ng/mL to 5.64ng/mL for C-Peptide, respectively. Populations sharing similar physical and socio-economic characteristics may adapt these intervals if validated and considered suitable for their laboratory methods

Asian J. Med. Biol. Res. September 2016, 2(3): 483-487

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Author Biography

Mainasara Abdullah Sulaiman, Department of Chemical Pathology & Immunology, College of Health Sciences, UDU



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Published

2016-11-04

How to Cite

Sulaiman, M. A., Gumel, D. S., Usman, U. Z., Ocheni, A. P., Abdulmumini, Y., Adanze, R. N., & Haruna, Y. M. (2016). Establishment of reference ranges for Serum Leptin and C-Peptide using enzymelinked immmunosorbent assay method: a preliminary report. Asian Journal of Medical and Biological Research, 2(3), 483–487. https://doi.org/10.3329/ajmbr.v2i3.30122

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Section

Short Communications