Antibiotic resistance pattern of Salmonella spp. isolated from stool samples of hospitalized diarrheal patients in Bangladesh

Authors

  • Mohammad Sharif Uddin Department of Microbiology, University of Chittagong, Chittagong
  • Md Imranul Hoq Department of Microbiology, University of Chittagong, Chittagong
  • Mohammad Shaokat Ali Department of Applied Chemistry and Chemical Technology, Faculty of Food Science and Technology, Chittagong Veterinary and Animal Sciences University, Khulshi, Chittagong-4225
  • Md Mijanur Rahman Department of Microbiology, University of Chittagong, Chittagong
  • KM Shariful Islam Department of Microbiology, University of Chittagong, Chittagong

DOI:

https://doi.org/10.3329/ajmbr.v3i4.35346

Keywords:

hospitalized diarrheal patients, stool samples, Salmonella spp., antibiotic resistance pattern

Abstract

This study was carried out to investigate the drug resistance pattern of Salmonella spp. from diarrheal patients of under 5 years of age. Collected stool samples from the hospitalized diarrheal patients were analyzed for the presence of Salmonella spp. Among 350 stool samples from diarrheal patients, 15 (4%) were positive for the Salmonella spp. Antibiotic susceptibility test of the identified Salmonella spp. was performed according to Kirby-Bauer disc diffusion method. Eight commonly used antibiotics including azithromycin (15 μg), chloramphenicol (30 μg), Sulphamethaxole-trimethoprim (25 μg), metronidazole (50 μg), tetracycline (30 μg), doxycycline (30 μg), erythromycin (15 μg) and ciprofloxacin (5 μg) used to determine drug resistance pattern of the identified Salmonella spp. Majority of the isolates were multidrug resistant showed resistance against more than three drugs. 73% of Salmonella spp. was resistant to 2-4 drugs and 20% showed resistance to more than 5 drugs. We found that 100% Salmonella showed resistance to metronidazole and 87% were resistant to erythromycin. 7% isolates were resistant to chloramphenicol and doxycycline and 20% were resistant to ciprofloxacin. Antibiotic resistance is a serious public health problem worldwide and a leading cause of mortality and morbidity. This kind of situation, leads to great socioeconomic losses from the perspective of the patient, the hospital, and the whole society. To get rid form the drug resistance problem unnecessary, over and misuse of antibiotics should immediately prohibited and policy of judicious use of antibiotics should be strengthened.

Asian J. Med. Biol. Res. December 2017, 3(4): 534-538

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Author Biography

Mohammad Sharif Uddin, Department of Microbiology, University of Chittagong, Chittagong



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Published

2018-01-30

How to Cite

Uddin, M. S., Hoq, M. I., Ali, M. S., Rahman, M. M., & Islam, K. S. (2018). Antibiotic resistance pattern of Salmonella spp. isolated from stool samples of hospitalized diarrheal patients in Bangladesh. Asian Journal of Medical and Biological Research, 3(4), 534–538. https://doi.org/10.3329/ajmbr.v3i4.35346

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Section

Short Communications