Effect of spirulina (Spirulina platensis) and vitamin E on arsenic induced toxicity in Quail
DOI:
https://doi.org/10.3329/ajmbr.v6i1.46483Keywords:
arsenic; spirulina; vitamin EAbstract
Chronic arsenic toxicity is a severe disease in men and animals which occurs severely in Bangladesh. Arsenic (As) contamination in ground water used in drinking is the major concern because arsenic is present in human and animal food chain. This work was done in quails with a view to observing the efficacy of spirulina (Spirulina platensis) and vitamin E for prevention of arsenic toxicity. 60 quails were used in this study and animals were divided into control group (T0), arsenic treated group (T1), arsenic plus spirulina treated group (T2) and arsenic plus vitamin E treated group (T3). Each group consists of 15 quails. Quails of T0 group were given normal feed and water and kept as control. Quails of T1, T2 and T3 were given 100 mg arsenic trioxide/L drinking water daily for 30 days. In addition to arsenic trioxide quails of group T2 and T3 were simultaneously fed with spirulina @ 1 gm/kg feed and vitamin E @ 400 mg /kg body weight up to 30 days respectively. Five quails from each group (T0, T1, T2 and T3) were sacrificed at 15 days interval in order to determine haematological parameters. Result showed that in group T1, body weight gain was minimum, whereas in group T2 and T3 the body weight gain in quails were better. Reduction of TEC and Hb values were observed in arsenic treated group T1. Whereas in rest groups the TEC and Hb values were comparatively higher than arsenic treated group. Noticeable change observed in liver and kindey of arsenic treated group in compare to the control group. Histopathological changes also observed in liver and kindey of arsenic treated group in compare to the control group. In conclusion, spirulina and vitamin E have significant effect on body weight, hematological and postmortem and histopathological changes.
Asian J. Med. Biol. Res. March 2020, 6(1): 93-98
Downloads
357
307
Downloads
Published
How to Cite
Issue
Section
License
Authors who publish with this journal agree to the following terms / The author(s) affirm(s) that:
- The manuscript submitted is based on authors own research and is original work.
- Authors certify that we all participated in the research work and preparation of the manuscript in a substantive way.
- Authors also declare that they have read and approved the manuscript.
- Authors further declare that the manuscript has not been published in part or full and is not being submitted or considered for publication in part or full elsewhere.
- Any material included in the manuscript does not violate copyright or other rights of anyone.
- Authors also affirm that the article contains no vilifying or unlawful statements and does not contain material or instructions that might cause harm or injury to the Editor-in-Chief/Editors of the Journal and the public.
- Authors assure Asian J. Med. Biol. Res. and the Editor-in-Chief/Editors of the Journals, and hold them harmless from any loss, expense or damage occurred by a claim or suit by a third party for copyright violation, or any suit arising out of any violation of the foregoing warranties as a result of publication of my/our article.
- In consideration of authors manuscript submitted, authors hereby grant Asian J. Med. Biol. Res. unlimited, worldwide, permanent royalty-free, right to publish, use, dispense, license, transmit, display, exhibit, record, store, translate, digitize, broadcast, reproduce and archive, in any format or medium, whether now known or developed hereafter.
All materials related to manuscripts, accepted or rejected, including photographs, original figures etc., will be kept by Asian J. Med. Biol. Res. for one year following the editors decision. These materials will then be destroyed.