Prevalence of urinary tract infections, associated risk factors, and antibiotic resistance pattern of uropathogens in young women at Noakhali, Bangladesh

Authors

  • Imam Hossain Department of Microbiology, Noakhali Science and Technology University, Noakhali-3814, Bangladesh
  • Sutapa Bhowmik Department of Microbiology, Noakhali Science and Technology University, Noakhali-3814, Bangl
  • Mohammad Sharif Uddin Department of Microbiology, Noakhali Science and Technology University, Noakhali-3814, Bangladesh
  • Popy Devnath Department of Microbiology, Noakhali Science and Technology University, Noakhali-3814, Bangladesh
  • Asma Akter Department of Microbiology, Noakhali Science and Technology University, Noakhali-3814, Bangladesh
  • Lutfun Nahar Eti Department of Microbiology, Noakhali Science and Technology University, Noakhali-3814, Bangladesh
  • Shakhawat Hussen Department of Microbiology, Noakhali Science and Technology University, Noakhali-3814, Bangladesh
  • Mohammad Maksudur Rahman Nayem Department of Microbiology, Noakhali Science and Technology University, Noakhali-3814, Bangladesh
  • Shahidur Rahman Department of Microbiology, Noakhali Science and Technology University, Noakhali-3814, Bangladesh
  • SM Sayem Department of Microbiology, Noakhali Science and Technology University, Noakhali-3814, Bangladesh
  • Md Towhidul Islam Department of Microbiology, Noakhali Science and Technology University, Noakhali-3814, Bangladesh

DOI:

https://doi.org/10.3329/ajmbr.v7i2.55000

Keywords:

urinary tract infection; uropathogen; antimicrobial resistance; young females; risk factors; Bangladesh

Abstract

Urinary tract infection (UTI) remains one of the most common infections among young females diagnosed in developing countries. The emergence of antibiotic resistance among uropathogens is a global problem. This study aimed to determine the prevalence and resistance of antibiotics to uropathogens, and to understand the relationship of uropathogens to multiple clinical, social and demographic factors of young female students in a university in Bangladesh. Four hundred freshly voided midstream urine samples collected from young female students and several clinical and socio-demographic variables along with UTI symptomatic queries were determined. Bacterial isolation was carried out by using standard and specific microbiological techniques and antimicrobial susceptibility pattern was determined by Kirby Bauer Disc diffusion method. Among the tested specimens, 106 (26.5%) has significant bacterial growth, 60 (57%) were symptomatic, and 46 (43%) were asymptomatic. The highest uropathogen was recorded within the age group of 24-25 years (51%). There was a significant association (p < 0.05) of uropathogen with anatomical abnormality of urinary tract, water sources for food preparation and bathing, and the number of person sharing the same toilet. Most predominantly isolated bacteria were E. coli (32.08%) followed by Staphylococcus saprophyticus (24.53%), Streptococcus spp. (16.04%), Klebsiella spp. (14.15%), Aceinetobacter spp. (4.72%), Citrobacter spp. (2.83%), Enterobacter spp. (2.83%), and Pseudomonas spp. (2.83%). In the effectiveness of each treated antibiotic, urinary pathogens were highly resistant towards nalidixic acid (80.19%), ampicillin (75.73%), cephalexin (70%) and azithromycin (68.48) while against imipenem (7.94%) and amikacin (18.87%) least resistancy were found. A good understanding of the etiology of uropathogens will assist the general practitioner to identify the correct therapeutic strategy for the proper management of UTIs.

Asian J. Med. Biol. Res. 2021, 7 (2), 202-213

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Published

2021-06-30

How to Cite

Hossain, I. ., Bhowmik, S. ., Uddin, M. S. ., Devnath, P. ., Akter, A. ., Eti, L. N. ., Hussen, S. ., Rahman Nayem, M. M. ., Rahman, S. ., Sayem, S. ., & Islam, M. T. . (2021). Prevalence of urinary tract infections, associated risk factors, and antibiotic resistance pattern of uropathogens in young women at Noakhali, Bangladesh. Asian Journal of Medical and Biological Research, 7(2), 202–213. https://doi.org/10.3329/ajmbr.v7i2.55000

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Research Articles