Rhino- Orbito- Cerebral- Mucormycosis with Osteomyelitis in a Patient with Diabetes mellitus: A Case Report and Literature Review

Authors

  • Rumana Habib Dept of Neurology, Ibrahim Medical college and BIRDEM General Hospital, Shahbag, Dhaka
  • Rashedul Islam Medical officer , Neurology, Ibrahim Medical college and BIRDEM General Hospital, Shahbag, Dhaka
  • Aminur Rahman Assistant Professor, Dept of Neurology, Ibrahim Medical college and BIRDEM General Hospital, Shahbag, Dhaka
  • NB Bhowmik Associate Professor, Dept of Neurology, Ibrahim Medical college and BIRDEM General Hospital, Shahbag, Dhaka
  • Amirul Haque Professor and Head, Dept of Neurology, Ibrahim Medical college and BIRDEM General Hospital, Shahbag, Dhaka

DOI:

https://doi.org/10.3329/birdem.v2i2.12331

Keywords:

Mucormycosis, Diabetes Mellitus

Abstract

Mucormycosis is a form of fulminant invasive fungal infection of the sinonasal tract that often extends to the orbit, brain, palate, and skin. It is caused by members of the order Mucorales, and it is considered to be the most fatal fungal infection known to man. It is most commonly associated with diabetic ketoacidosis, hematologic malignancies, acquired immunodeficiency syndrome acquired immunodeficiency syndrome, see AIDS. , and immunosuppressive therapy. This rare opportunistic infection exists in many forms, the most common of which is rhinocerebral mucormycosis. Treatment includes aggressive surgical debridement of the necrotic tissue combined with systemic antifungal therapy. In this case report, we describe the successful management of rhinoorbitocerebral mucormycosis, a subtype of the rhinocerebral variety, complicated by osteomyelitis of cranium. We review the diagnostic work-up and discuss the literature with respect to the presentation, pathophysiology, management, and outcome of the disease.

DOI: http://dx.doi.org/10.3329/birdem.v2i2.12331

(Birdem Med J 2012; 2(2):124-127)

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Published

2012-10-22

How to Cite

Habib, R., Islam, R., Rahman, A., Bhowmik, N., & Haque, A. (2012). Rhino- Orbito- Cerebral- Mucormycosis with Osteomyelitis in a Patient with Diabetes mellitus: A Case Report and Literature Review. BIRDEM Medical Journal, 2(2), 124–128. https://doi.org/10.3329/birdem.v2i2.12331

Issue

Section

Case Reports