Effects of chlorella vulgaris supplementation on oxidative stress, erythrogram, and leukogram profiles in gallus  gallus domesticus with molecular docking analysis

Authors

  • Zain Ul Abideen Institute of Zoology, Bahauddin Zakariyya University, Multan, Pakistan
  • Abdullah A Alamri Physical Sciences Department, Chemistry Division, College of Science, Jazan University, P.O. Box. 114, Jazan 45142, Kingdom of Saudi Arabia
  • Mohammad A Jareebi Department of Family and Community Medicine, Faculty of Medicine, Jazan University, Jazan 45142, Saudi Arabia.
  • Muhammad Farooq Department of Zoology, Ghazi University, Dera Ghazi Khan, Pakistan.
  • Aleem Ahmed Khan Institute of Zoology, Bahauddin Zakariyya University, Multan, Pakistan
  • Mujahid Hussain Department of Zoology, The University of Lahore. Punjab, Pakistan.
  • Khalid M Elazab Department of Biology, College of Science, Jazan University, P.O. Box. 114, Jazan 45142, Saudi Arabia.
  • Mohamed M Alawlaqi Department of Biology, College of Science, Jazan University, P.O. Box. 114, Jazan 45142, Saudi Arabia.
  • A El-Shabasy Department of Biology, College of Science, Jazan University, P.O. Box. 114, Jazan 45142, Saudi Arabia.
  • Mohamed Mostafa Soliman Department of Biology, College of Science, Jazan University, P.O. Box. 114, Jazan 45142, Saudi Arabia; Department of Zoology, Faculty of Science, Ain Shams University, Cairo, PO Box 11566, Egypt.

Keywords:

Isoquinoline, Erythrogram, Leukogram, Antioxidancy, 3S3Q protein

Abstract

This study evaluated the effects of Chlorella vulgaris supplementation on oxidative stress, erythrogram, and leukogram parameters in 378 Gallus gallus domesticus (hens) assigned to six groups: control (C) and experimental (G1-G5). Over 71 days, blood samples were analyzed for serum metabolites, plasma minerals, antioxidant markers [glutathione (GSH), catalase (CAT), superoxide dismutase (SOD), total antioxidant capacity (TAC), protein carbonyl (PCO), malondialdehyde (MDA)], and hematological profiles. Chlorella supplementation significantly enhanced TAC, SOD, and GSH, while reducing MDA and PCO in a dose-dependent manner. Erythrocyte and leukocyte profiles also improved, indicating strengthened antioxidant defenses and immune responses, with higher doses exerting greater effects. Molecular docking further confirmed nutrient efficiency through interactions between isoquinoline and 3S3Q protein.

Bangladesh J. Bot. 55(2): 371-379, 2026 (June)

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Published

2026-06-29

How to Cite

Effects of chlorella vulgaris supplementation on oxidative stress, erythrogram, and leukogram profiles in gallus  gallus domesticus with molecular docking analysis. (2026). Bangladesh Journal of Botany, 55(2), 371-379. https://banglajol.info/index.php/BJB/article/view/91201

Issue

Vol. 55 No. 2 (2026)

Section

Articles

License

© Bangladesh Botanical Society

Authors are required to transfer the copyright of their articles to the journal. The Declaration form is available here http://www.bdbotsociety.org/journal/journal_pdf/declaration_form.pdf

How to Cite

Effects of chlorella vulgaris supplementation on oxidative stress, erythrogram, and leukogram profiles in gallus  gallus domesticus with molecular docking analysis. (2026). Bangladesh Journal of Botany, 55(2), 371-379. https://banglajol.info/index.php/BJB/article/view/91201