RDWI is Better Discriminant than RDW in Differentiation of Iron Deficiency Anaemia and Beta Thalassaemia Trait

Authors

  • Ayatun Nesa Assistant Professor, Department of Pathology, Ibrahim Medical College, Dhaka
  • Md Abu Tayab Junior Consultant, Department of Paediatrics Medicine, Dhaka Shishu Hospital, Dhaka
  • Tuhin Sultana Assistant Professor, Department of Clinical Pathology, BSMMU, Dhaka
  • Lubna Khondker Assistant Professor, Department of Medical Statistics, BSMMU, Dhaka
  • Md Quddusur Rahman Associate Professor, Department of Clinical Pathology, BSMMU, Dhaka
  • Md Anwarul Karim Associate Professor, Department of Paediatric Haematooncology, BSMMU, Dhaka
  • AN Nashimuddin Ahmed Professor and Chairman, Department of Clinical Pathology, BSMMU, Dhaka

DOI:

https://doi.org/10.3329/bjch.v33i3.5690

Keywords:

Microcytic hypochromic anemia, discrimination indices

Abstract

Iron deficiency anemia (IDA) and beta-thalassemia trait (BTT) are the common causes
of microcytic hypochromic anaemia. Several discrimination indices have been
introduced to discriminate quickly these similar entities via parameters obtained from
automated cell counter. The purpose of the study was to compare the value of two
discrimination indices, red cell distribution width index (RDWI) and red cell distribution
width (RDW) in differentiation of BTT and IDA. This study consists of 57 cases of
BTT and 72 cases of IDA. Severe anaemia (<7.0 gm/dl) had been excluded because
these cases are not confused with BTT cases in practice. Sensitivity, specificity,
positive and negative predictive values and Youden’s index of both indices in
differentiation of BTT and IDA had been calculated. RDWI appears to be reliable and
useful index for differentiation of iron deficiency anaemia and beta thalassaemia trait.
Again RDWI is better than RDW in differentiating BTT from IDA.

Key words: Microcytic hypochromic anemia; discrimination indices.

DOI: 10.3329/bjch.v33i3.5690

Bangladesh Journal of Child Health 2009; Vol.33(3): 100-103

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How to Cite

Nesa, A., Tayab, M. A., Sultana, T., Khondker, L., Rahman, M. Q., Karim, M. A., & Ahmed, A. N. (2010). RDWI is Better Discriminant than RDW in Differentiation of Iron Deficiency Anaemia and Beta Thalassaemia Trait. Bangladesh Journal of Child Health, 33(3), 100–103. https://doi.org/10.3329/bjch.v33i3.5690

Issue

Vol. 33 No. 3 (2009)

Section

Original Articles