Antimicrobial Susceptibility Pattern of Streptococcus pneumoniae among Healthy Carrier Children under Five Years Old attended at Outpatient Department of Largest Teaching Hospital in Bangladesh

Authors

  • Moonmoon Shormin Assistant Professor, Department of Microbiology, Shaheed Monsur Ali Medical College, Dhaka, Bangladesh
  • SM Shamsuzzaman Professor, Head of the department, Department of Microbiology, Dhaka Medical College, Dhaka, Bangladesh
  • Samira Afroz Assistant Professor, Department of Microbiology, Ad-din Women’s Medical College, Dhaka, Bangladesh
  • Asif Rashed Assistant Professor, Department of Microbiology, Mugda Medical College, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/bjid.v8i1.57950

Keywords:

Antimicrobial agent; susceptibility; Streptococcus pneumoniae; invasive pneumococcal diseases (IPD); pneumococcal vaccine

Abstract

Background: Over the past several decades, antimicrobial resistance in Streptococcus pneumoniae has dramatically increased worldwide.

Objectives: The purpose of the present study was to detect and monitor the antibiotic susceptibility pattern of Streptococcus pneumoniae among under five years old children as carrier.

Methodology: The cross-sectional study was conducted in the Department of Microbiology of Dhaka Medical College Hospital (DMCH), Dhaka, Bangladesh from July 2016 to June 2017 Data were collected among 200 under five children from Pediatric OPD of Dhaka Medical College Hospital. Streptococcus pneumoniae were isolated and identified by culture, Gram staining and biochemical test. Antimicrobial susceptibility test for S. pneumoniae was performed by disc-diffusion method.

Results: Out of 200 nasopharyngeal swabs, 67(33.50%) isolates were positive by culture. Among 67 isolated Streptococcus pneumoniae, all the isolates were susceptible to penicillins, cephalosporins, glycopeptides and carbapenems. Among the isolated Streptococcus pneumoniae, 92.53% isolates were susceptible to ciprofloxacin, 52.16% isolates were susceptible to erythromycin and azithromycin. Streptococcus pneumoniae showed very low susceptibility to gentamicin (11.94%) and co-trimoxazole (23.88%).

Conclusion: This study has shown the antimicrobial susceptibility pattern of Streptococcus pneumoniae in children as carriers.

Bangladesh Journal of Infectious Diseases June 2021;8(1):12-17

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Published

2022-01-30

How to Cite

Shormin, M. ., Shamsuzzaman, S., Afroz, S. ., & Rashed, A. (2022). Antimicrobial Susceptibility Pattern of Streptococcus pneumoniae among Healthy Carrier Children under Five Years Old attended at Outpatient Department of Largest Teaching Hospital in Bangladesh. Bangladesh Journal of Infectious Diseases, 8(1), 12–17. https://doi.org/10.3329/bjid.v8i1.57950

Issue

Vol. 8 No. 1 (2021)

Section

Original Articles

License

Copyright (c) 2021 Moonmoon Shormin, SM Shamsuzzaman, Samira Afroz, Asif Rashed

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Copyright

Copyright on any research article in the Bangladesh Journal of Infectious Diseases is retained by the author(s).

The authors grant the Bangladesh Infection Research Association a license to publish the article and identify itself as the original publisher.

Articles in the Bangladesh Journal of Infectious Diseases are Open Access articles published under the Creative Commons CC BY-NC License (https://creativecommons.org/licenses/by-nc/4.0/)

This license permits use, distribution and reproduction in any medium, provided the original work is properly cited, and it is not used for commercial purposes.