Cutaneous Leishmaniasis in El-Madinna Manowra region, Saudi Arabia in 2012.

Authors

  • Nazar M Abdalla College of Medicine, King Khalid University, Abha,
  • Abdelgani M Abdelgani Faculty of Medical Lab. , Gezira University, Wad Medani, P.O.BOX 20,
  • Amani A Osman Family & Community Medicine Department, College of Medicine, King Khalid University, 61421 Abha, P.O. 641,
  • Mohamed A Sarhan Department of Biology, College of Science, King Khalid University, 61413 Abha P.O. Box 9004

DOI:

https://doi.org/10.3329/bjms.v12i3.13189

Keywords:

Cutaneous Leishmaniasis, L. tropica, L. (L) major, Skin lesion, Polymerase chain reactions (PCR)

Abstract

Objective: Leishmaniasis is a parasitic disease causing major public health problem in form of visceral and cutaneous types. The cutanoue leishmaniasis is caused by L. tropica, in low-land areas without reservoir; Arthroponatic leishmaniasis (ACL),  Zoonotic Cutaneous Leishmaniasis ( ZCL), in high-land. This case report involved; 25 years old Egyptian active young single male adult, stayed in Utama (75 Km far from El-Madina Manowra on the road to Makkah). He presented with three skin lesions on his arms occurred within the last 1-3 months. on examination revealed; volcano- like indurated ulcers which clinically suspected as leishmania lesions .

Materials and Methods: Laboratory investigations were involved; skin smear using Giemsa stain, Leishmanin test (LST),  polymerase chain reaction (PCR), sequencing and phylogenitic analysis BLAST (NCBI).

Results: Microscopy  positive LDB (leishmanin donovani bodies), Leishmanin test (LST) was negative. PCR  positive L. major . Sequence alignment were 100% with nine Iranian isolates and one Tunisian isolate. After one month of treatment with Pentostam (Sodium stibogluconate) local injections at the site of lesions the lesion progressed from ulcer to scar.

Conclusion: L. major is a major species causing cutaneous leishmaniasis in Al-Medina Manowra region in Saudi Arabia. The usage of the polymerase chain reaction (PCR) is a useful diagnostic tool and help to identify the causative species.

Bangladesh Journal of Medical Science Vol. 12 No. 03 July 13 Page 325-330

DOI: http://dx.doi.org/10.3329/bjms.v12i3.13189

 

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Published

2013-06-23

How to Cite

Abdalla, N. M., Abdelgani, A. M., Osman, A. A., & Sarhan, M. A. (2013). Cutaneous Leishmaniasis in El-Madinna Manowra region, Saudi Arabia in 2012. Bangladesh Journal of Medical Science, 12(3), 325–330. https://doi.org/10.3329/bjms.v12i3.13189

Issue

Vol. 12 No. 3 (2013)

Section

Case Reports

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