Atypical Leiomyoma: a rare histologic variant - A Diagnostic Challenge

Authors

  • Mukta Pujani Associate Professor, Pathology, ESIC Medical College, Faridabad Formerly at: Hamdard Institute of Medical Sciences and Research (HIMSR), New Delhi
  • Mohammad Jaseem Hassan Associate Professor, Pathology, Hamdard Institute of Medical Sciences and Research (HIMSR), New Delhi
  • Safia Rana Assistant Professor, Pathology, Hamdard Institute of Medical Sciences and Research (HIMSR), New Delhi
  • Sujata Jetley Professor & Head, Pathology, Hamdard Institute of Medical Sciences and Research (HIMSR), New Delhi

DOI:

https://doi.org/10.3329/bjms.v17i3.37011

Keywords:

atypical leiomyoma, bizarre leiomyoma, symplastic leiomyoma

Abstract

Bizarre or atypical leiomyoma (LM) is defined as “leiomyoma containing giant cells with pleomorphic nuclei and little or no mitotic activity.” Due to the ominous and worrisome microscopic appearance (many large giant cells with hyperchromatic, pleomorphic, malignant looking nuclei), this variant maybe misdiagnosed as a sarcoma. It, therefore presents a diagnostic challenge to the pathologist to accurately diagnose such a tumor while ensuring that a true malignancy is not overlooked. We report a case of a atypical leiomyoma of the uterus in a 40 year old female presenting with irregular menstrual bleeding. This highlights the need for extensive tissue sampling in such dubious cases to help arrive at a correct diagnosis.

Bangladesh Journal of Medical Science Vol.17(3) 2018 p.511-514

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Author Biography

Mukta Pujani, Associate Professor, Pathology, ESIC Medical College, Faridabad Formerly at: Hamdard Institute of Medical Sciences and Research (HIMSR), New Delhi



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Published

2018-06-29

How to Cite

Pujani, M., Hassan, M. J., Rana, S., & Jetley, S. (2018). Atypical Leiomyoma: a rare histologic variant - A Diagnostic Challenge. Bangladesh Journal of Medical Science, 17(3), 511–514. https://doi.org/10.3329/bjms.v17i3.37011

Issue

Vol. 17 No. 3 (2018)

Section

Case Reports

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