The Effect of Bitter Melon (Momordica charantia L.) Leaves Extractonon Glycated Albumin in Diabetic Foot Ulcers: Randomized Controlled Trial

Authors

  • Fahrun Nur Rosyid Department of Medical-Surgical Nursing, School of Nursing, Universitas Muhammadiyah Surakarta, Surakarta, Indonesia
  • Tomy Adi Prasetyo Department of Medical-Surgical Nursing, School of Nursing, Universitas Muhammadiyah Surakarta, Surakarta, Indonesia
  • Chlara Yunita Prabawati Department of Medical-Surgical Nursing, School of Nursing, Universitas Muhammadiyah Surakarta, Surakarta, Indonesia
  • - Supratman Department of Community Nursing, School of Nursing, Universitas Muhammadiyah Surakarta, Surakarta, Indonesia
  • - Sugiarto Division of Endocrinology and Metabolism, Department of Internal Medicine Dr. Moewardi General Hospital of Surakarta, Indonesia
  • K Heri Nugroho HS Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Diponegoro University, Semarang, Indonesia

DOI:

https://doi.org/10.3329/bjms.v20i2.51536

Keywords:

Bitter melon, Momordica charantia L., glycated albumin levels, diabetes mellitus, diabetic foot ulcer

Abstract

Objective: This study aims to prove the effect of supplementation of bitter melon leaves extract on glycemic status in diabetic foot ulcer (DFU).

Materials and Methods: This study used a randomized, double-blinded, and placebo-controlled trial. Thirty DFU patients based on PEDIS 1-8 scores who met the criteria were divided into 2 groups consisting of 15 patients as a treatment group with the administration of bitter melon leaves extract at a dose of 6 g/day and 15 patients as a control group of with placebo. This intervention was conducted in 4 weeks. Glycemic status was measured by the value of glycated albumin and examined at baseline and at the end of treatment. Data were analyzed using paired t-test and independent t-test.

Results: After 4 weeks of treatment, there was an increase in the baseline value of glycated albumin in the treatment group from 24.5 ± 11.7% to 25.8 ± 12.7% or an increase of 1.3 ± 6.3% and a decrease in the control group from 27.5 ± 13.1% to 25.8 ± 8.5% or a decrease of 1.7 ± 12.4%. The results of the analysis of the effect of supplementation of bitter melon leaves extract on the value of glycated albumin were not significant (p = 0.99).

Conclusion: The supplementation of bitter melon leaf extract with a dose of 6 g / day did not significantly affect the value of glycated albumin.

Bangladesh Journal of Medical Science Vol.20(2) 2021 p.281-287

Downloads

Download data is not yet available.
Abstract
660
PDF
534

Downloads

Published

2021-02-01

How to Cite

Rosyid, F. N., Prasetyo, T. A., Prabawati, C. Y., Supratman, .-., Sugiarto, .-., & HS, K. H. N. (2021). The Effect of Bitter Melon (Momordica charantia L.) Leaves Extractonon Glycated Albumin in Diabetic Foot Ulcers: Randomized Controlled Trial. Bangladesh Journal of Medical Science, 20(2), 281–287. https://doi.org/10.3329/bjms.v20i2.51536

Issue

Vol. 20 No. 2 (2021)

Section

Original Articles

License

Authors who publish in the Bangladesh Journal of Medical Science agree to the following terms that:

  1. Authors retain copyright and grant Bangladesh Journal of Medical Science the right of first publication of the work.

  2. Creative Commons Licence
    Articles in Bangladesh Journal of Medical Science are licensed under a Creative Commons Attribution 4.0 International License CC BY-4.0.This license permits use, distribution and reproduction in any medium, provided the original work is properly cited.
  3. Authors are able to enter into separate, additional contractual arrangements for the distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  4. Authors are permitted to post their work online (e.g., in institutional repositories or on their website) as it can lead to productive exchanges, as well as greater citation of published work.