The prevalence of olfactory dysfunction and its associated factors in patients with COVID-19 infection: A Hospital-based study

Authors

  • Md Mehedi Hasan Assistant Professor, Department of ENT and Head Neck Surgery, Ibn Sina Medical College Hospital, Dhaka, Bangladesh
  • Naima Ahmed Tamanna Department of Statistics, Jagannath University, Dhaka, Bangladesh
  • Mohammad Nasimul Jamal Consultant, Department of ENT & Head Neck Surgery, Square Hospitals Ltd., Dhaka, Bangladesh
  • Abu Naser Md Jamil Associate Professor (CC), Department of ENT and Head Neck Surgery, Ibn Sina Medical College Hospital, Dhaka, Bangladesh
  • Md Jamal Uddin Department of Statistics, Shahjalal University of Science and Technology, Sylhet, Bangladesh. and Department of General Education Development (GED), Daffodil International University, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/bjms.v22i1.63079

Keywords:

COVID-19; Anosmia; Olfactory Dysfunction; Factors; Bangladesh

Abstract

Background: The coronavirus disease of 2019 (COVID-19) is a global viral pandemic that originated in East Asia (China) and is quickly spreading to every corner of the globe. In Bangladesh, no research has been conducted on olfactory dysfunction in COVID-19 infected patients and its associated factors. We aimed to determine the correlation between olfactory dysfunction (OD), particularly anosmia and COVID-19 infected patients’ demographic and clinical characteristics.

Methods: We conducted a hospital based prospective observational study. We collected patients’ information, including laboratory-confirmed COVID-19 test results from a COVID dedicated hospital, Square Hospitals Ltd., Dhaka, Bangladesh. We used the Pearson Chi-square test and logistic regression model to assess the associations between demographic and clinical characteristics and OD (i.e. anosmia).

Results: Out of 600 COVID-19 positive patients, 38.7% were diagnosed with OD. We found that patients’ age, smoking status, cough, dyspnea, sore throat, asthenia, and nausea or vomiting were significantly associated with anosmia. We observed smoking patients were 1.73 times more likely to experience anosmia than non-smoking patients Odd ratio (OR)=1.73, 95% confidence interval (CI) = 1.01-2.98]. Interestingly, our data showed that the risk of developing anosmia was greater in younger patients than in older patients, and this risk decreased as age increased (OR) range for different age groups: 1.26 to 1.08]. In addition, patients who complained of asthenia had a significantly double risk of developing anosmia [OR = 1.96, CI = 1.23-3.06].

Conclusions: Our study shows that 38.7% of patients diagnosed with OD. Patients’ age, smoking status, and asthenia are significantly positively associated with anosmia. Since anosmia can be a significant marker for the diagnosis of COVID-19, we suggest regular screening of OD in patients with early symptoms of COVID-19, particularly younger patients, smokers, and who complained of asthenia.

Bangladesh Journal of Medical Science Vol. 22 No. 01 January’23 Page : 195-204

Downloads

Download data is not yet available.
Abstract
29
PDF
56

Downloads

Published

2023-01-01

How to Cite

Hasan, M. M. ., Tamanna, N. A. ., Jamal, M. N. ., Md Jamil, A. N. ., & Uddin, M. J. . (2023). The prevalence of olfactory dysfunction and its associated factors in patients with COVID-19 infection: A Hospital-based study. Bangladesh Journal of Medical Science, 22(1), 195–204. https://doi.org/10.3329/bjms.v22i1.63079

Issue

Vol. 22 No. 1 (2023)

Section

Original Articles

License

Copyright (c) 2022 Md Mehedi Hasan, Naima Ahmed Tamanna, Mohammad Nasimul Jamal, Abu Naser Md Jamil, Md Jamal Uddin

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish in the Bangladesh Journal of Medical Science agree to the following terms that:

  1. Authors retain copyright and grant Bangladesh Journal of Medical Science the right of first publication of the work.

  2. Creative Commons Licence
    Articles in Bangladesh Journal of Medical Science are licensed under a Creative Commons Attribution 4.0 International License CC BY-4.0.This license permits use, distribution and reproduction in any medium, provided the original work is properly cited.
  3. Authors are able to enter into separate, additional contractual arrangements for the distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  4. Authors are permitted to post their work online (e.g., in institutional repositories or on their website) as it can lead to productive exchanges, as well as greater citation of published work.