Comparative in-vitro evaluation of ebastine tablets (10 mg) available in bangladesh

Authors

  • Syeda Fahria Hoque Mimmi School of Pharmacy, Brac University, Dhaka, Bangladesh.
  • Saqib Rahman School of Pharmacy, Brac University, Dhaka, Bangladesh.
  • Prethula Areefin Department of Pharmaceutical Sciences, North South University, Dhaka 1229, Bangladesh.
  • Md Shaki Mostaid Department of Pharmaceutical Sciences, North South University, Dhaka 1229, Bangladesh.
  • Md Ayman Siddique Rufaida Research Foundation, Mohammadpur, Dhaka 1207, Bangladesh.
  • Md Aminul Haque School of Pharmacy, Brac University, Dhaka, Bangladesh and Rufaida Research Foundation, Mohammadpur, Dhaka 1207, Bangladesh.

DOI:

https://doi.org/10.3329/bjms.v23i1.70673

Keywords:

Ebastine; Friability; Disintegration time; Dissolution profile; Potency

Abstract

Background: The symptoms of allergic responses, such as hay fever or urticaria, can be relieved with the use of ebastine, an efficient anti-allergic medication.

Objective & Method: This study’s primary objective was to assess and contrast various quality control parameters, such as weight variation, % friability, hardness, disintegration time, dissolution profile, and potency, of the twelve different brands of Ebastine tablets that were readily available in Bangladesh in accordance with compendia procedures. It’s interesting to note that, according to various official requirements, all of the quality parameters indicated above were within acceptable bounds.

Conclusion: Therefore, doctors can advise patients to use any of the Ebastine brands that are sold in Bangladesh.

Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 47-53

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Published

2024-01-02

How to Cite

Mimmi, S. F. H. ., Rahman, S. ., Areefin, P. ., Mostaid, M. S. ., Siddique, M. A. ., & Haque, M. A. . (2024). Comparative in-vitro evaluation of ebastine tablets (10 mg) available in bangladesh. Bangladesh Journal of Medical Science, 23(1), 47–53. https://doi.org/10.3329/bjms.v23i1.70673

Issue

Vol. 23 No. 1 (2024)

Section

Original Articles

License

Copyright (c) 2024 Syeda Fahria Hoque Mimmi, Saqib Rahman, Prethula Areefin, Md Shaki Mostaid, Md Ayman Siddique, Md Aminul Haque

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