Bibliometric Analysis of Clinical Trials on Mouthwashes published in PubMed (1967-2024)

Authors

  • Namrata Dagli Center for Global Health Research, Saveetha Medical College, Saveetha Institute of Medical, Dental & Technical Sciences, Chennai, Tamil Nadu, India
  • Mainul Haque Unit of Pharmacology, Faculty of Medicine and Defence Health, Universiti Pertahanan Nasional Malaysia (National Defence University of Malaysia), Kuala Lumpur, Malaysia
  • Santosh Kumar Department of Periodontology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, Gujarat, India

DOI:

https://doi.org/10.3329/bjms.v24i1.78606

Keywords:

Mouthwashes, Clinical Trials, Oral Health, Bibliometrics, Publication Trends, Collaboration, Authorship, Journals, Thematic shifts, Dental Hygiene, Preventive Dentistry, VOSviewer, Biblioshiny, PubMed

Abstract

Mouthwashes have been extensively studied through clinical trials to assess their efficacy in improving oral health. This bibliometric analysis explores research trends, key contributors, collaborative networks, and thematic evolution in this field. The online search was performed in the PubMed database on August 29, 2024, using relevant keyword- string to identify relevant publications. After applying inclusion and exclusion criteria, 1,883 articles published between 1967 and 2024 were selected and analyzed using the bibliometric software VOSviewer and Biblioshiny. The coauthorship analysis identified several key collaborators: Addy M has the highest total link strength (TLS) value of 112. The Journal of Clinical Periodontology emerged as a leading journal, publishing 220 clinical trials on mouthwashes. The USA dominated the research output, followed by Brazil and India. In addition, Brazil showed the highest levels of international collaboration. The thematic analysis suggests that the focus of mouthwash clinical trials shifted from examining basic antibacterial efficacy and formulation to exploring personalized, long-term health effects and incorporating mouthwash into broader oral health and wellness strategies, including psychological aspects. The analysis also revealed that international partnerships are still limited while the field is highly collaborative, with only 5.79% of studies involving cross-border cooperation. This highlights potential areas for growth in advancing global research collaborations. The analysis also suggests that the field has evolved substantially. However, some areas are still underexplored, such as studies on the environmental impact of chronic mouthwash use and its effects on the natural balance of mouth bacteria, which warrant more attention.

Bangladesh Journal of Medical Science Vol. 24 No. 01 January’25 Page : 17-32

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Published

2025-01-07

How to Cite

Dagli , N., Haque , M., & Kumar , S. (2025). Bibliometric Analysis of Clinical Trials on Mouthwashes published in PubMed (1967-2024). Bangladesh Journal of Medical Science, 24(1), 17–32. https://doi.org/10.3329/bjms.v24i1.78606

Issue

Vol. 24 No. 1 (2025)

Section

Review Article

License

Copyright (c) 2025 Namrata Dagli , Mainul Haque , Santosh Kumar

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