Evaluation of Serum Thyrotropin and Urinary Protein level among Pre-eclamptic Pregnancies

Abstract

Objective: This study was done to evaluate serum thyrotropin (thyroid stimulating hormone,TSH) and urinary protein level among preeclamptic pregnancies.

Patients and methods: This study was conducted at the Institute of Nuclear medicine and Allied Sciences, Rajshahi along with Department of Gynecology & Obstetrics, Rajshahi Medical College Hospital, Rajshahi during the period between 1^st July, 2011 and 31^st June, 2013.Total 66 preeclamptic pregnant patients who were referred for the assay of serum thyrotropin hormone level were included as sample under the basis of non-random purposive sampling technique. Their age, urinary protein level and level of serum thyrotropin hormone were recorded and analyzed.

Results: Among the total enrolled preeclamptic pregnant patients (n=66), Mean (± SD) age was 27 ± 3.88 years (range=19 to 35 years). Regarding urinary protein level, 26 (39.39 %) patients had 1+ urinary protein level and 40 (60.61%) patients had ≥ 2+ urinary protein level. Serum thyrotropin level was 6.16 ± 0.85 (mean ± SD) among total 66 patients. Among the preeclamptic pregnant patients having 1+ urinary protein level,  thyrotropin level was 5.38 ± 0.70 (mean ± SD) and 6.67 ± 0.49 (mean ± SD) among the patients having  ≥ 2+ urinary protein level.

Conclusion: Thyrotropin level is higher in preeclamptic pregnant patients and reflects severity of preeclampsia.

Bangladesh J. Nuclear Med. 19(2): 120-122, July 2016