Baseline PET-CT evaluation of Bone Marrow-Liver-Spleen Type of Diffuse Large B-Cell Lymphoma: A Rare Aggressive Extranodal Lymphoma

Authors

  • Sadia Hossain Institute of Nuclear Medicine and Allied Science (INMAS), Dhaka.
  • Farhana Rahman Institute of Nuclear Medicine and Allied Science (INMAS), Dhaka.
  • Rawnak Afrin Institute of Nuclear Medicine and Allied Science (INMAS), Dhaka.
  • Afroza Afrin Institute of Nuclear Medicine and Allied Science (INMAS), Dhaka.
  • Shanker Biswas Institute of Nuclear Medicine and Allied Science (INMAS), Dhaka.
  • Tanima Biswas Institute of Nuclear Medicine and Allied Science (INMAS), Dhaka.
  • Tania Sultana Institute of Nuclear Medicine and Allied Science (INMAS), Dhaka.
  • Sabrina Islam Institute of Nuclear Medicine and Allied Science (INMAS), Dhaka.
  • Shaila Sharmin Institute of Nuclear Medicine and Allied Science (INMAS), Dhaka.
  • Rubina Begum Institute of Nuclear Medicine and Allied Science (INMAS), Dhaka.
  • Mohona Hossain Institute of Nuclear Medicine and Allied Science (INMAS), Dhaka.
  • Jasmine Ara Haque Institute of Nuclear Medicine and Allied Science (INMAS), Dhaka.
  • Asif Rashed Mugda Medical College.

DOI:

https://doi.org/10.3329/bjnm.v27i1.71526

Keywords:

Bone marrow-liver-spleen (BLS) subtype of diffuse large B-cell lymphoma (DLBCL), extra nodal lymphoma, hemophagocytic lymphohistiocytosis (HLH), 18F-FDG PET

Abstract

Bone marrow-liver-spleen (BLS) type lymphoma is a rare subgroup of diffuse large B-cell lymphoma, characterized by bone marrow involvement without lymph nodes. Symptoms include fever, anemia, and hemophagocytic lymphohistiocytosis. Early diagnosis and treatment are crucial for proper management and prevention. We report a case of a 59-year-old male with diffuse large B-cell lymphoma (DLBCL) involving bone marrow. He was diagnosed with a bone marrow-liver-spleen (BLS) subtype of lymphoma with the help of F-18 FDG PET-CT. BLS is an unusual subgroup of extra-nodal DLBCL. Very few cases have been reported to date. The disease showed unique clinico-pathological features of involvement of bone marrow with or without liver and/or spleen, but no lymph node or other extra-nodal sites are involved, hence the name BLS.

Bangladesh J. Nuclear Med. 27(1): 112-116, 2024

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Published

2024-06-23

How to Cite

Hossain, S., Rahman, F., Afrin, R., Afrin, A., Biswas, S., Biswas, T., Sultana, T., Islam, . S. . ., Sharmin, S. ., Begum, R. ., Hossain, M. ., Haque, J. A. ., & Rashed, A. . (2024). Baseline PET-CT evaluation of Bone Marrow-Liver-Spleen Type of Diffuse Large B-Cell Lymphoma: A Rare Aggressive Extranodal Lymphoma. Bangladesh Journal of Nuclear Medicine, 27(1), 112–116. https://doi.org/10.3329/bjnm.v27i1.71526

Issue

Vol. 27 No. 1 (2024)

Section

Case Reports

License

All rights reserved to Editor-in-Chief, Bangladesh Journal of Nuclear Medicine, Society of Nuclear Medicine, Bangladesh