Tiny Tumor with a Bigger Challenge: A Journey Through Uncertainty Using Neuro-Endoscopy in a Case of Recurrent Cushing Disease

Authors

  • Md Shahidur Rahman Sikder Assistant Professor, Stroke and Endovascular Surgery, Department of Neurosurgery, Dhaka Medical College Hospital, Dhaka, Bangladesh
  • Tanbir Siddique Department of Neurosurgery, DMCH
  • Abu Hasan  Department of Neurosurgery, Dhaka Medical College Hospital, Dhaka, Bangladesh
  • Md Sujon Sharif Assistant Professor, Clinical Neurosurgery, Department of Neurosurgery, DMCH
  • Bashir Ahmed Residential Neurosurgeon, National Institute of Neuroscience Hospital, Dhaka
  • Md Motassimul Hassan Associate Professor, Stroke and Endovascular Surgery, Department of Neurosurgery, DMCH

DOI:

https://doi.org/10.3329/bjns.v14i2.89031

Keywords:

Cushing disease; ACTH-secreting pituitary adenoma; Pituitary microadenoma; Recurrent  pituitary adenoma; Endoscopic endonasal transsphenoidal surgery; Reoperative pituitary  surgery; Surgical anatomy distortion; Cortisol hypersecretion  Case

Abstract

Cushing disease caused by ACTH-secreting pituitary microadenomas remains a surgical  challenge, especially in recurrent cases with distorted anatomy. We report a case of a  35-year-old male with recurrent Cushing disease following unsuccessful initial transsphenoidal  surgery. Re-operated using endoscopic endonasal transsphenoidal approach, this  case illustrates the complexity of navigating scarred anatomical landmarks and ensuring  complete tumor excision. The patient demonstrated marked clinical and biochemical  improvement postoperatively, emphasizing the importance of meticulous surgical  technique in reoperative endoscopic pituitary surgery(Cappabianca et al., 2014; Losa et  al., 2000).  

Bang. J Neurosurgery 2025; 14(2): 138-141                                 

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Published

2026-04-23

How to Cite

Sikder, M. S. R., Siddique, T., Hasan, A., Sharif, M. S., Ahmed, B., & Md Motassimul Hassan. (2026). Tiny Tumor with a Bigger Challenge: A Journey Through Uncertainty Using Neuro-Endoscopy in a Case of Recurrent Cushing Disease. Bangladesh Journal of Neurosurgery, 14(2), 138–141. https://doi.org/10.3329/bjns.v14i2.89031

Issue

Vol. 14 No. 2 (2025)

Section

Case Reports

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Copyright (c) 2025 Bangladesh Society of Neurosurgeons

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