Evaluation of Serum parathyroid hormone level measurement in total thyroidectomy patients

Authors

  • Islam MS Assistant professor, Department of Laboratory Medicine, BSMMU, Bangladesh
  • Sultana T Associate professor, Department of Laboratory Medicine, BSMMU, Bangladesh.
  • Paul D Associate professor, Department of Laboratory Medicine, BSMMU, Bangladesh
  • Huq AHMZ Associate professor, Department of Otolaryngology, BSMMU, Dhaka
  • Ferdoushi S Assistant professor, Department of Laboratory Medicine, BSMMU, Dhaka
  • Chawdhury AA Associate professor, Department of Otolaryngology, BSMMU, Dhaka
  • Rahman MQ Chairman and Professor, Department of Laboratory Medicine, BSMMU
  • Ahmed SU Professor, Department of Surgery, BSMMU, Dhaka
  • Ahmed ANN Professor, Department of Laboratory Medicine, BSMMU

DOI:

https://doi.org/10.3329/bjo.v23i1.45105

Keywords:

Serum parathyroid hormone, Total thyroidectomy

Abstract

Background: Postoperative hypoparathyroidism is a common complication after total thyroidectomy. It is necessary to diagnose hypoparathyroidism immediately after total thyroidectomy for minimizing complications.

Objective: The objective of this study was to measure and to evaluate the serum parathyroid hormone level in total thyroidectomy patients.

Methods: This prospective observational study was carried out in the Department of Clinical Pathology in collaboration with Department of Surgery & Department of Otolaryngology of BSMMU and Department of Otolaryngology of DMCH, Dhaka, during the period of September 2010 to August 2011.

Results: Total 65 patients were studied irrespective of age and sex. Decreased serum PTH was found in 9 cases and normal parathyroid hormone was found in 56 cases. Male was 16.0% and female was 84.0%. Females were predominant. The incidence of hypoparathyroidism was 41.5%. Asymptomatic hypoparathyroidism was found in 8 and symptomatic hypoparathyroidism was found in 1 cases. Decreased serum PTH was developed mostly in malignant thyroid diseases. In relation to preoperative PTH values, intraoperative PTH levels were lower from 5.48% to 90.0%, (mean±SD in percentage is 65.3±16.7, p=.001) which is significant in paired t test. The mean difference of intraoperative (20 minutes after total thyroidectomy), parathyroid hormone levels were statistically significant (p<0.05) between patient with decreased parathyroid hormone and patient with normal parathyroid hormone in unpaired t-test.

Conclusion: Serum parathyroid hormone level significantly decreased 20 minutes after total thyroidectomy. If clinical sign symptoms of hypoparathyroidism are not developed in postoperative period, patient is safe and can be discharged from hospital.

Bangladesh J Otorhinolaryngol; April 2017; 23(1): 5-10

Downloads

Download data is not yet available.
Abstract
22
PDF
32

Downloads

Published

2020-01-23

How to Cite

MS, I., T, S., D, P., AHMZ, H., S, F., AA, C., MQ, R., SU, A., & ANN, A. (2020). Evaluation of Serum parathyroid hormone level measurement in total thyroidectomy patients. Bangladesh Journal of Otorhinolaryngology, 23(1), 5–10. https://doi.org/10.3329/bjo.v23i1.45105

Issue

Vol. 23 No. 1 (2017)

Section

Original Articles

License

Manuscripts submitted for publication in the Bangladesh Journal of Otorhinolaryngology must not have been previously submitted or published. Accepted papers become the permanent property of the Bangladesh Journal of Otorhinolaryngology. By submitting a manuscript, the authors(s) agree that copyrights for their articles are automatically transferred to Bangladesh Journal of Otorhinolaryngology, if and when the articles are accepted for publication.

The use, in this journal, of registered trade names, trade marks, etc. without special acknowledgement does not imply that such names, as defined by the relevant protection laws, be regarded as unprotected, and, thus, free for general use.

Authors who publish with this journal agree to the following terms:

 

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).