Voice Outcomes of Autologous Fat Injection Laryngoplasty for Unilateral Vocal Fold Paralysis.
DOI:
https://doi.org/10.3329/bjo.v31i1.84289Keywords:
injection laryngoplasty; unilateral vocal fold paralysis; autologous fat; Voice Handicap Index (VHI)Abstract
Background: Autologous fat injection laryngoplasty is a surgical procedure for unilateral vocal fold paralysis (UVFP) to medialize the nonfunctioning vocal fold to allow for complete glottic closure and, thus, improve phonation, protect the airway and improve
symptoms of aspiration and dysphagia.
Objective: This study compares the pre-and postoperative voice outcomes of autologous fat injection laryngoplasty in patients with UVFP.
Materials and Methods: A prospective observational study was conducted in the Department of Otolaryngology-Head & Neck Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka, from January 2021 to June 2022, with
20 patients having UVFP. The subjects were selected based on inclusion and exclusion criteria. Diagnosis of UVFP was identified by indirect laryngoscopy (IL) and confirmed by Fiber Optic Laryngoscopy (FOL). Patients were investigated by Voice Handicap Index (VHI) scores at four-time points: (1) Day before operation (T0), (2) 3 days post injection (T1), (3) 1 month post injection (T2), and (4) 3 months post injection (T3). All the VHI information was recorded in a prefixed questionnaire to analyze and calculate
the results.
Results: The age of the patients ranged from 19-55 years, with a mean age of 38.8±9.93 years. Among them, 13 were female (65%), and 7 were male (35%). Male: Female ratio was 1:1.8. Most patients (55%) had thyroid surgery, and the rest were idiopathic (45%). 75% of the vocal cord are paralyzed on the left side and 25% on the right-sided. The VHI scores improved significantly from 75.85±13.04 preoperatively to 58.70±12.38 at 3 days postoperatively (P < 0.0001); 47.50±9.51 at 1 month postoperatively (P < 0.0001), and 37.35±8.50 at 3 months postoperatively (P < 0.0001).
Conclusion: Autologous fat injection laryngoplasty is a simple, safe, and cost-effective temporary phonosurgical procedure for the treatment of unilateral vocal fold paralysis, thus improving acoustic and voice-related quality of life (QOL).
Bangladesh J Otorhinolaryngology 2025; 31 (1) Page- 05-15
Downloads
0
0
Downloads
Published
How to Cite
Issue
Section
License
Manuscripts submitted for publication in the Bangladesh Journal of Otorhinolaryngology must not have been previously submitted or published. Accepted papers become the permanent property of the Bangladesh Journal of Otorhinolaryngology. By submitting a manuscript, the authors(s) agree that copyrights for their articles are automatically transferred to Bangladesh Journal of Otorhinolaryngology, if and when the articles are accepted for publication.
The use, in this journal, of registered trade names, trade marks, etc. without special acknowledgement does not imply that such names, as defined by the relevant protection laws, be regarded as unprotected, and, thus, free for general use.
Authors who publish with this journal agree to the following terms:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
