Formulation and evaluation of loratadine mouth dissolving tablet
DOI:
https://doi.org/10.3329/bjsir.v48i2.15745Keywords:
Loratadine, Mouth dissolving, Direct compression, Wetting time, Croscarmellose sodiumAbstract
Loratadine 10 mg mouth dissolving tablet (MDT) was prepared by using super disintegrant such as sodium starch glycollate, crosscarmellose sodium, crospovidone at various concentration, aspartame was used as sweetening agent. The excipients were used for this study was based on the compatibillity studies. All the formulation was prepared by direct compression method. Among all the formulations crospovidone at 10 mg/tab gives 99.1% drug release at end of 12th min. It was considered as optimized batch. The optimized batch was processed for all the evaluation parameter and stability studies. The final formulations were packed in blister package.
Bangladesh J. Sci. Ind. Res. 48(2), 137-142, 2013
Downloads
132
92
Downloads
Published
How to Cite
Issue
Section
License
Bangladesh Council of Scientific and Industrial Research (BCSIR) holds the copyright to all contents published in Bangladesh Journal of Scientific and Industrial Research (BJSIR). A copyright transfer form should be signed by the author(s) and be returned to BJSIR.
The entire contents of the BJSIR are protected under Bangladesh Council of Scientific and Industrial Research (BCSIR) copyrights.
BJSIR is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC) Creative Commons Attribution-NonCommercial 4.0 International License which allows others remix, tweak, and build upon the articles non-commercially, and although their new works must also acknowledge and be non-commercial, they dont have to license their derivative works on the same terms.