Chemical and Antioxidant Studies of <i>Citrus macroptera</i>

Authors

  • Sadia A Chowdhury Department of Pharmacy, Stamford University, Dhaka-1217
  • M Hossain Sohrab Analytical Research Division, Bangladesh Council of Scientific and Industrial Research Laboratories (BCSIR), Dhaka- 1205
  • Bidyut K Datta Department of Pharmaceutical Engineering and Technology, University of Dhaka, Dhaka-1000
  • Choudhury M Hasan Bangladesh Council of Scientific and Industrial Research (BCSIR), Dhaka-1205

DOI:

https://doi.org/10.3329/bjsir.v43i4.2235

Keywords:

Citrus macroptera, Rutaceae, Lupeol, Stigmasterol, Antioxidant

Abstract

Lupeol (1) and Stigmasterol (2) were isolated from the crude extracts of the stem bark of Citrus macroptera (Family: Rutaceae) for the first time. The n-hexane, dichloromethane and methanol extracts were screened in vitro for antioxidant activity using the 1, 1-diphenyl-2-picrylhydrazyl-hydrate (DPPH) free radical scavenging assay. The hot methanol extract showed potential antioxidant activity (IC50: 178.96 μg/ml) whereas the cold methanol and dichloromethane extracts showed moderate activity (IC50: 242.78 μg/ml and 255.78 μg/ml respectively). Mild antioxidant activity was observed with the n-hexane extract of the stem bark of Citrus macroptera (IC50: 422.94 μg/ml).

Key words: Citrus macroptera, Rutaceae, Lupeol, Stigmasterol, Antioxidant.  

doi: 10.3329/bjsir.v43i4.2235

Bangladesh J. Sci. Ind. Res. 43(4), 449-454, 2008

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How to Cite

Chowdhury, S. A., Sohrab, M. H., Datta, B. K., & Hasan, C. M. (2009). Chemical and Antioxidant Studies of <i>Citrus macroptera</i>. Bangladesh Journal of Scientific and Industrial Research, 43(4), 449–454. https://doi.org/10.3329/bjsir.v43i4.2235

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Articles