Studies on Antibacterial and Antifungal Activities and Minimum Inhibitory Concentrations of Mixed Ligand Transition Metal Complexes of Dibasic Acids as Primary and Heterocyclic Bases as Secondary Ligands

Authors

  • MA Akbor BCSIR Laboratories, Dhaka. Dhanmondi, Dhaka
  • MS Islam Department of Chemistry, University of Rajshahi, Rajshahi
  • N Akhter Department of Chemistry, University of Rajshahi, Rajshahi
  • S Ahmed BCSIR Laboratories, Dhaka. Dhanmondi, Dhaka
  • S Siraj BCSIR Laboratories, Dhaka. Dhanmondi, Dhaka

DOI:

https://doi.org/10.3329/bjsir.v46i3.9044

Keywords:

Mixed Ligand, Transition metal, Antimicrobial Activity, Antifungal Activity Minimum Inhibitory Concentrations (MIC)

Abstract

Mixed ligand (diphenic/ adipic as primary Ligand and quinoline / 8 - hydroxyquinoline as secondary) transition metal complexes of Cobalt (II), Cupper (II), Rhodium (III) and Platinum (IV) ions were synthesized and characterized. Their antibacterial activities against ten bacteria had been evaluated by the disc diffusion method,whilst their antifungal activities against two fungi had been also evaluated by the same method. Minimum inhibitory concentrations (MIC) had been evaluated against six bacteria. The MIC of the complexes against Shigella dysenteriae, Samonella typhi, Streptococcus-β-haemolyticus and Bacillus megaterium were 32 μg/ml; whilst Escherichia coli and Samonella typhi-A the MIC of Co (II) and Pt (IV) were 32μg/ml and those of Cu(II) and Rh(III) complexes were 64 μg/ml. It was found that Cobalt (II), Cupper (II) & Rhodium (III) complexes had pronounced antibacterial and antifungal activities. Platinum (IV) complex had moderate antibacterial and antifungal activity. These values indicate that these are active compounds.

Key words: Mixed Ligand; Transition metal; Antimicrobial Activity; Antifungal Activity Minimum Inhibitory Concentrations (MIC)

DOI: http://dx.doi.org/10.3329/bjsir.v46i3.9044

BJSIR 2011; 46(3): 365-368

Downloads

Download data is not yet available.
Abstract
788
PDF
573

Downloads

How to Cite

Akbor, M., Islam, M., Akhter, N., Ahmed, S., & Siraj, S. (2011). Studies on Antibacterial and Antifungal Activities and Minimum Inhibitory Concentrations of Mixed Ligand Transition Metal Complexes of Dibasic Acids as Primary and Heterocyclic Bases as Secondary Ligands. Bangladesh Journal of Scientific and Industrial Research, 46(3), 365–368. https://doi.org/10.3329/bjsir.v46i3.9044

Issue

Vol. 46 No. 3 (2011)

Section

Articles

License

Bangladesh Council of Scientific and Industrial Research (BCSIR) holds the copyright to all contents published in Bangladesh Journal of Scientific and Industrial Research (BJSIR). A copyright transfer form should be signed by the author(s) and be returned to BJSIR.

The entire contents of the BJSIR are protected under Bangladesh Council of Scientific and Industrial Research (BCSIR) copyrights.

Creative Commons Licence
BJSIR is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC) Creative Commons Attribution-NonCommercial 4.0 International License which allows others remix, tweak, and build upon the articles non-commercially, and although their new works must also acknowledge and be non-commercial, they don’t have to license their derivative works on the same terms.