Spot urinary protein/osmolality ratio as a predictor for proteinuria of nephrotic range

Authors

  • Salma Jahan
  • Md. Saiful Islam
  • Md. Moazzam Hossain

DOI:

https://doi.org/10.3329/bmrcb.v33i2.1207

Keywords:

Kidney, Proteinuria, Urinary

Abstract

A prospective study was carried out on 50 patients (age 1-15 years) with nephrotic range of proteinuria to determine the correlation of 24-hour urinary total protein with spot urinary protein/creatinine ratio and urinary protein/osmolality ratio. Another 50 patients having no proteinuria grouped as control. Twenty-four hours urine and spot urine were collected from each child and were analyzed for total volume, total protein, creatinine and osmolality level. The average 24-hour urinary total proteins in nephritic patient were 2148.6 ± 808.7 mg and the spot urinary protein/creatinine and spot urinary protein/osmolality were 3.2332 ± 0.4293 mg/mg and 3.2418 ± 0.4393 mg/mOsm respectively. There was a strong positive correlation of the 24-hour urinary total protein with spot urinary protein/creatinine and protein/osmolality ratios (r=0.9846 and 0.9870, p= <0.001). But in control group, these ratios did not show any correlation with 24-hour urinary total protein. These results suggest that in pediatric patients with nephrotic range of proteinuria, the spot urinary protein/osmolality ratio can predict the 24-hour  urinary total protein excretion like that of spot urinary protein/creatinine ratios.

Keywords: Kidney; Proteinuria; Urinary

DOI: 10.3329/bmrcb.v33i2.1207

Bangladesh Med Res Counc Bull 2007; 33: 65-68

Downloads

Download data is not yet available.
Abstract
139
PDF
383

Downloads

How to Cite

Jahan, S., Islam, M. S., & Hossain, M. M. (2008). Spot urinary protein/osmolality ratio as a predictor for proteinuria of nephrotic range. Bangladesh Medical Research Council Bulletin, 33(2), 65–68. https://doi.org/10.3329/bmrcb.v33i2.1207

Issue

Vol. 33 No. 2 (2007)

Section

Research Papers

License

Authors who publish with this journal agree to the following terms.

Authors retain copyright and grant the journal right of first publication.

Creative Commons Licence
Articles in the Bangladesh Medical Research Council Bulletin are licensed under a Creative Commons Attribution 4.0 International License (CC-BY) that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).