In vitro antioxidant potential study of some synthetic quinoxalines

Authors

  • MM Hossain Associate Professor, Department of Chemistry, Jahangirnagar University, Savar, Dhaka
  • MM Hossain Student, Department of Chemistry, Jahangirnagar University, Savar, Dhaka
  • MH Muhib Associate Professor, Department of Chemistry, Jahangirnagar University, Savar, Dhaka
  • MR Mia Associate Professor, Department of Chemistry, Jahangirnagar University, Savar, Dhaka
  • S Kumar Department of Pharmacy, Jahangirnagar University, Savar, Dhaka
  • SA Wadud Department of Ophthalmology, Bangabhandhu Sheikh Mujib Medical University, Dhaka

DOI:

https://doi.org/10.3329/bmrcb.v38i2.12880

Keywords:

antioxidant potential

Abstract

In continuation of our study the in vitro antioxidant activity of some novel quinoxaline derivatives was investigated by 1,1-diphenyl-2-picrylhydrazyl (DPPH) method with respect to ascorbic acid. To determine the antioxidant activity, a number of substituted indoxyls (3A-G), cyclic ketones (2A-G), and quinoxalines (1A-G) were synthesized by both microwave and conventional heating methods. The present findings revealed that some quinoxalines and their precursors (1D, 1F, 1G and 2E) exhibited a marked scavenging effect on DPPH radical.

DOI: http://dx.doi.org/10.3329/bmrcb.v38i2.12880

Bangladesh Med Res Counc Bull 2012; 38: 47-50

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Published

2012-12-09

How to Cite

Hossain, M., Hossain, M., Muhib, M., Mia, M., Kumar, S., & Wadud, S. (2012). In vitro antioxidant potential study of some synthetic quinoxalines. Bangladesh Medical Research Council Bulletin, 38(2), 47–50. https://doi.org/10.3329/bmrcb.v38i2.12880

Issue

Vol. 38 No. 2 (2012)

Section

Research Papers

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