Effect of tonsillectomy on humoral immunity

Authors

  • M Nasrin Department of Microbiology, Bangladesh Medical College, Dhaka
  • MRA Miah Department of Microbiology and Immunology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka
  • PG Datta Department of Otolaryngology, BSMMU, Dhaka
  • AA Saleh Department of Microbiology and Immunology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka
  • S Anwar Department of Microbiology and Immunology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka
  • KL Saha Department of Otolaryngology, BSMMU, Dhaka

DOI:

https://doi.org/10.3329/bmrcb.v38i2.12882

Keywords:

tonsillectomy, humoral immunity

Abstract

Tonsils are one of the important secondary lymphoid organ in immune system. It remains controversial whether tonsillectomy results in decreased serum immunoglobulin level. The purpose of this study was to observe the effect of tonsillectomy on humoral immunity parameters among the patients with tonsillar disease. Total group A 70 patients up to the age of 18 years, who were enrolled for tonsillectomy and 30 age matched children group B were included for comparative study. Serum IgG, IgM and IgA levels were measured in all 70 patients before tonsillectomy and in 56 patients who came for 1st follow-up after one month and 30 patients who came for 2nd follow up after three months of tonsillectomy. Serum IgG, IgM and IgA levels were also measured in group B children. Serum IgG, IgM and IgA levels in patients of group A did not show any significant difference in comparison to group B. One month after tonsillectomy the level of IgG was slightly decreased and IgM and IgA were increased compared to preoperative value but not statistically significant. All IgG, IgM and IgA were also not significantly altered in comparison to group B. Three months after tonsillectomy serum IgG, IgM and IgA level were found decreased in comparison to pre operative value and group B, among which difference of only IgG was significant. After tonsillectomy humoral parameters were found reduced but overall impact on humoral immune status was not significantly altered.

DOI: http://dx.doi.org/10.3329/bmrcb.v38i2.12882

Bangladesh Med Res Counc Bull 2012; 38: 59-61

Downloads

Download data is not yet available.
Abstract
209
PDF
554

Downloads

Published

2012-12-09

How to Cite

Nasrin, M., Miah, M., Datta, P., Saleh, A., Anwar, S., & Saha, K. (2012). Effect of tonsillectomy on humoral immunity. Bangladesh Medical Research Council Bulletin, 38(2), 59–61. https://doi.org/10.3329/bmrcb.v38i2.12882

Issue

Vol. 38 No. 2 (2012)

Section

Research Papers

License

Authors who publish with this journal agree to the following terms.

Authors retain copyright and grant the journal right of first publication.

Creative Commons Licence
Articles in the Bangladesh Medical Research Council Bulletin are licensed under a Creative Commons Attribution 4.0 International License (CC-BY) that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).