Community acquired pneumonia in diabetic and non-diabetic hospitalized patients: presentation, causative pathogens and outcome

Authors

  • MAA Saibal Department of Medicine, Eastern Medical College Hospital, Comilla
  • SHZ Rahman Immunology & Molecular Biology, National Institute of Cancer Research & Hospital (NICRH), Dhaka
  • L Nishat Department of Anatomy, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka
  • NH Sikder Neurology, Northern International Medical College, Dhaka
  • SA Begum Department of Radiology & Imaging, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine & Metabolic Disorders (BIRDEM), Dhaka
  • MJ Islam Cancer Epidemiology, NICRH, Dhaka,
  • KN Uddin Internal Medicine, BIRDEM, Dhaka

DOI:

https://doi.org/10.3329/bmrcb.v38i3.14336

Keywords:

acquired pneumonia, diabetic, non-diabetic, causative pathogens,

Abstract

Both community acquired pneumonia and diabetes mellitus are common in Bangladesh. Though hospitalization of diabetic patients with CAP is increasing, data regarding their clinical presentation, microbial characteristics, antimicrobial susceptibility and outcome are lacking. This study was aimed at finding any difference in clinical presentation, bacterial causes, antimicrobial susceptibility pattern of isolated bacteria and outcome in diabetic and non-diabetic hospitalized patients with CAP. In this study total 47 diabetic and 43 non-diabetic adult hospitalized patients with CAP were enrolled. Clinical presentation of CAP differed in diabetics and non-diabetics. Frequency of atypical presentation and CURB-65 score were significantly higher in diabetics. Pleural effusion with multilobar infiltration was also common feature for CAP in diabetic patients. Klebsiella pneumoniae was the most frequent causative pathogen for CAP in diabetic patients, whereas Streptococcus pneumoniae was the most frequent causative agent for non-diabetic patients. Bacteria isolated from sputum sample of diabetic patients with CAP were resistant to almost all recommended antibiotics used for CAP but 100% of isolates were sensitive to Carbapenems. Pulmonary complications were relatively more in diabetics than in non-diabetics. Hospitalized diabetics with CAP required referral to intensive care unit more than that of non-diabetics. So, diabetic patients with CAP need extra attention.

DOI: http://dx.doi.org/10.3329/bmrcb.v38i3.14336

Bangladesh Med Res Counc Bull 2012; 38(3): 98-103 (December)

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Published

2013-03-30

How to Cite

Saibal, M., Rahman, S., Nishat, L., Sikder, N., Begum, S., Islam, M., & Uddin, K. (2013). Community acquired pneumonia in diabetic and non-diabetic hospitalized patients: presentation, causative pathogens and outcome. Bangladesh Medical Research Council Bulletin, 38(3), 98–103. https://doi.org/10.3329/bmrcb.v38i3.14336

Issue

Vol. 38 No. 3 (2012)

Section

Research Papers

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