Leptin to adiponectin ratio in preeclampsia

Authors

  • A Khosrowbeygi School of Medicine, Lorestan University of Medical Sciences, Khorramabad
  • H Ahmadvand School of Medicine, Lorestan University of Medical Sciences, Khorramabad

DOI:

https://doi.org/10.3329/bmrcb.v39i1.15805

Keywords:

Leptin, adiponectin, preeclampsia

Abstract

The aim of the present study was to assess leptin/adiponectin ratio in preeclamptic patients compared with normal pregnant women. A cross-sectional study was designed. The study population consisted of 30 preeclamptic patients and 30 healthy pregnant women. Serum levels of total leptin and adiponectin were assessed using commercially available enzyme-linked immunosorbent assay methods. The oneway ANOVA and Students t tests and Pearsons correlation analysis were used for statistical calculations. Levels of leptin and adiponectin were also adjusted for BMI. A p-value <0.05 was considered statistically significant. The leptin/adiponectin ratio was increased significantly in preeclamptic patients. The leptin/adiponectin ratio was significantly higher in severe preeclamptic patient than in mild preeclampsia. Adjusted leptin/adiponectin ratio was also significantly increased in preeclamptic patients than in normal pregnant women. The findings of the present study suggest that the leptin/adiponectin ratio was increased in preeclamsia and imbalance between the adipocytokines could be involved in the pathogenesis of preeclampsia.

DOI: http://dx.doi.org/10.3329/bmrcb.v39i1.15805

Bangladesh Med Res Counc Bull 2013; 39: 18-21

Downloads

Download data is not yet available.
Abstract
177
PDF
186

Downloads

Published

2013-07-24

How to Cite

Khosrowbeygi, A., & Ahmadvand, H. (2013). Leptin to adiponectin ratio in preeclampsia. Bangladesh Medical Research Council Bulletin, 39(1), 18–21. https://doi.org/10.3329/bmrcb.v39i1.15805

Issue

Vol. 39 No. 1 (2013)

Section

Research Papers

License

Authors who publish with this journal agree to the following terms.

Authors retain copyright and grant the journal right of first publication.

Creative Commons Licence
Articles in the Bangladesh Medical Research Council Bulletin are licensed under a Creative Commons Attribution 4.0 International License (CC-BY) that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).