Elevated serum ?hCG and dyslipidemia in second trimester as predictors of subsequent Pregnancy Induced Hypertension

Authors

  • MP Mallick Department of Obstetrics and Gynaecology, Midnapore Medical College and Hospital, Paschim Medinipur, West Bengal
  • S Ray Department of Obstetrics and Gynaecology, Midnapore Medical College and Hospital, Paschim Medinipur, West Bengal
  • R Medhi Department of Obstetrics and Gynaecology, Silchar Medical College and Hospital, Silchar, Assam
  • S Bisai Society for Applied Studies (WHO Collaborating centre), Salt Lake, Kolkata, West Bengal

DOI:

https://doi.org/10.3329/bmrcb.v40i3.25230

Abstract

Objectives: To test the hypothesis that pregnant women with high serum ?hCG level and serum dyslipidemia in second trimester are more prone to develop subsequent Pregnancy Induced Hypertension (PIH). Materials & Methods: One hundred pregnant women with singleton pregnancy between 14 and 20 weeks of gestation attending antenatal outpatient department (OPD) of SMCH were studied. Serum ?hCG was estimated by two-site chemiluminescent-immunometric method. Serum lipid profile was evaluated by enzymatic colorimetric test with Lipid Clearing Factor (LCF). Results: Eighteen cases developed PIH while eighty two cases remained normotensive. The serum ?hCG level was significantly high (p?0.001) in those women developing PIH. Serum concentration of total cholesterol in women who subsequently developed PIH was significantly higher than that of normotensive group (p ?0.05). Mean TG value in PIH group was higher than the normotensive group. Level of LDL in PIH group was also significant (p?0.05). Conclusion: Present study showed that elevated serum ?hCG and Dyslipidemia in second trimester can be considered as predictors of subsequent PIH / Pre-eclampsia. However, there is need of large community based prospective study to validate the result.

Bangladesh Med Res Counc Bull 2014; 40 (3): 97-101

Downloads

Download data is not yet available.
Abstract
191
PDF
300

Author Biography

MP Mallick, Department of Obstetrics and Gynaecology, Midnapore Medical College and Hospital, Paschim Medinipur, West Bengal



Downloads

Published

2015-10-05

How to Cite

Mallick, M., Ray, S., Medhi, R., & Bisai, S. (2015). Elevated serum ?hCG and dyslipidemia in second trimester as predictors of subsequent Pregnancy Induced Hypertension. Bangladesh Medical Research Council Bulletin, 40(3), 97–101. https://doi.org/10.3329/bmrcb.v40i3.25230

Issue

Vol. 40 No. 3 (2014)

Section

Research Papers

License

Authors who publish with this journal agree to the following terms.

Authors retain copyright and grant the journal right of first publication.

Creative Commons Licence
Articles in the Bangladesh Medical Research Council Bulletin are licensed under a Creative Commons Attribution 4.0 International License (CC-BY) that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).