Splenic Volume: Correlation between Ultrasonogram and Standard CT Measurements

Abstract

Evaluation of splenic enlargement is important in the diagnosis and management of various diseases including liver disease, lymphoma and other primary or metastatic neoplasm. This cross sectional study was conducted in the department of radiology and imaging in Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM) from July 2007 to June 2009. The main objective of the study was to find out a more accurate sonographic measurement of splenic volume that well correlate with gold standard computed tomography (CT) volume. A total of 228 subjects were included in the study. All the subjects underwent ultrasound and CT examinations for measurement of splenic volume. The mean splenic volume measured by AVL (average length) was 182.62±80.28 cm³ (mean±SD) with range of 45.61-590.93 cm³ and by CT scan was 190.18±77.77 cm³ (mean±SD) with range of 46.52-565.81cm³. Most of the subjects 138(60.5%) had splenic volume 101-200 cm³. Splenic volume was evaluate by CT findings of 228 cases and expressed in cm³. Sonographic splenic volumes were calculated by using the prolate Ellipsoid method AVL (average length) and also expressed in cm³.The mean difference of splenic volume evaluated by CT and sonography was 7.43±5.39 cm³ with standard deviation of 5.39 cm³ measured from average length (AVL). The mean difference of splenic volume evaluated by two modalities measured by average length was statistically significant (pp<0.001).