Potency Determination of Essential Drug Samples Manufactured By Medium and Small Pharmaceutical Industries in Bangladesh

Authors

  • ABM Faruque University of Dhaka, Dhaka.
  • Homaira Fatema Ononna University of Dhaka.
  • ASM Monjur Al Hossain University of Dhaka, Dhaka.
  • Amlan Ganguly University of Dhaka, Dhaka.

DOI:

https://doi.org/10.3329/bmrcb.v43i2.35195

Keywords:

Drug potency, Small pharmaceutical industries, Sub-standard drugs

Abstract

Drugs are considered highly essential and sensitive items for saving lives. Pharmaceutical sector in Bangladesh has grown from strength to strength over the last 40 years and evolved from an import dependent to self-reliant, export oriented sector. But counterfeit, adulterated and sub-standard drugs, though small in percentage, still remain to be a threat in the local market. The purpose of this study is to determine potency of some essential drugs, which are used vigorously by sub-urban and rural people and manufactured by randomly selected small and medium pharmaceutical industries of Bangladesh. The study revealed that the measured potency of different essential drugs manufactured by randomly selected small pharmaceutical industries is mostly unsatisfactory. Here, it has been found that most of the drug samples did not match with the acceptance level: the potency of Amoxicillin tryhydrate capsule has been found 8.25%, 47.9%, 51.1% 19.06%, 57.06% from five different pharmaceutical industries and for Diclofenac Sodium is 44.9%, 26.8%, 27.2%, 29.9%, 19.4%, 62.12%, 15.9% and 60.76% from eight different industries. So, the Drug Administration should have a strict monitoring and controlling mechanism to the distribution of those drugs, otherwise the overall public health of the country will be at stake.

Downloads

Download data is not yet available.
Abstract
699
PDF
2131 ONLINE VIEW
1002

Author Biographies

ABM Faruque, University of Dhaka, Dhaka.

Pharmaceutical Technology

Homaira Fatema Ononna, University of Dhaka.

Pharmaceutical Technology

ASM Monjur Al Hossain, University of Dhaka, Dhaka.

Pharmaceutical Technology

Amlan Ganguly, University of Dhaka, Dhaka.

Pharmaceutical Technology

Published

2018-01-04

How to Cite

Faruque, A., Ononna, H. F., Al Hossain, A. M., & Ganguly, A. (2018). Potency Determination of Essential Drug Samples Manufactured By Medium and Small Pharmaceutical Industries in Bangladesh. Bangladesh Medical Research Council Bulletin, 43(2), 87–93. https://doi.org/10.3329/bmrcb.v43i2.35195

Issue

Section

Research Papers