Prevalence of anticardiolipin antibody in Bangladeshi patients with recurrent pregnancy loss

Authors

  • A.S.M. Giasuddin
  • Ishrat Mazhar
  • A.M. Mujibul Haq

DOI:

https://doi.org/10.3329/bmrcb.v36i1.5446

Keywords:

Antibody, Anticardiolipin, Bangladeshi, Recurrent pregnancy loss

Abstract

The objective of the present study was to see the prevalence of anticardiolipin antibody (ACA) in Bangladeshi patients (35) with recurrent pregnancy loss. Thirty-seven women with normal pregnancy were included as control. Serum levels (mean ± SD) of ACA (u/mL) was significantly higher, whereas ANA (Ab-index) and anti-dsDNA (Ab-index) were similar in cases compared to controls (Cases vs Controls g ACA: 31.8 ± 24.3 vs 10.5 ± 3.4, p<0.001; ANA: 1.07 ± 0.34 vs 0.92 ± 0.15, p>0.5; A-dsDNA: 0.53 ± 0.16 vs 0.52 ± 0.18, p>0.5). The cases positive for ACA, ANA and anti-dsDNA were 37.1% (p<0.001), 20% (p>0.05) and 2.8% (p>0.1) respectively. Among the seropositive cases 4/35 (11.4%) and 4/13 (30.8%) were positive for both ACA and ANA. In controls only 2/37 (5.4%) and 2/37 (5.4%) were positive for ACA and ANA respectively and none were positive for both ACA and ANA together simultaneously. Significantly high proportion of cases had O positive blood group (23/35: 65.7%, 10/13: 76.9%) (p<0.01). The prevalence of ACA varies according to population being 37.1% (13/35) in our patients with recurrent pregnancy loss and 5.4% in controls.

Online: 13 July 2010

DOI: http://dx.doi.org/10.3329/bmrcb.v36i1.5446

Bangladesh Med Res Counc Bull 2010; 36: 10-13


 

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How to Cite

Giasuddin, A., Mazhar, I., & Haq, A. M. (2010). Prevalence of anticardiolipin antibody in Bangladeshi patients with recurrent pregnancy loss. Bangladesh Medical Research Council Bulletin, 36(1), 10–13. https://doi.org/10.3329/bmrcb.v36i1.5446

Issue

Vol. 36 No. 1 (2010)

Section

Research Papers

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