Organisms isolated from wound swab and pus with their antibiotic susceptibility pattern in a tertiary care hospital in Bangladesh.

Antibiogram of organisms from wound infection

Authors

  • Mohammad Jobayer Department of Microbiology, National Center for Control of Rheumatic Fever & Heart Disease, Sher-E-Bangla Nagar, Dhaka, Bangladesh.
  • Mizanur Rahman Department of Microbiology, Dhaka Medical College, Dhaka, Bangladesh.
  • Nadira Akter Department of Microbiology, Dhaka Medical College, Dhaka, Bangladesh.
  • Naomee Shareef Department of Microbiology, Dhaka Medical College, Dhaka, Bangladesh.
  • Rubina Afroz Rana Department of Microbiology, National Center for Control of Rheumatic Fever & Heart Disease, Dhaka, Bangladesh.
  • SM Shamsuzzaman Department of Microbiology, Dhaka Medical College, Dhaka, Bangladesh.

DOI:

https://doi.org/10.3329/bmrcb.v47i2.57777

Keywords:

Antibiotic susceptibility, Pus, Resistance, Wound swab

Abstract

Background: Antimicrobial resistance is a global health problem and the number of organisms developing resistance to commonly used antibiotics is increasing.

Objective: The study was aimed to find out the pattern of common organism isolated from wound swabs and pus with their antibiogram.

Methods: This observational study was conducted from September 2018 to January 2019 in a tertiary care hospital in Dhaka, Bangladesh. Culture and sensitivity tests were done for wound swabs and pus samples. Data regarding information of the patients, isolated organisms and culture and sensitivity reports were collected from the records of the department of microbiology.

Results: Out of 1709 samples, 72.0% yielded growth of organisms of which 86.4% were gram negative and 13.6% were gram positive bacteria. Pseudomonas spp was the most commonly (43.8%) isolated organism from both wound swab and pus samples followed by Escherichia coli (16.6%), Staphylococcus aureus (11.8%), Klebsiella spp (9.8%). Among gram negative bacteria, 14.9% were ESBL producing organisms and Klebsiella spp were the most commonly isolated ESBL producers. Most of the bacteria showed high resistance to commonly used antibiotics. Gram negative bacteria were mostly resistant to amoxicillin followed by fluoroquinolones, co-trimoxazole, and cephalosporins whereas colistin, carbapenems and piperacillin/tazobactum were the most effective drugs against them. Majority of gram positive bacteria were resistant to fluoroquinolones and co-trimoxazole but 100% Staphylococcus aureus were sensitive to vancomycin, followed by linezolid (98.0%) and teicoplanin (86.0%) and 32.0% of them were Methicillin resistant (MRSA).

Conclusion: The susceptibility pattern shows that some common antibiotics, especially antibiotics of oral form have very limited usefulness in treatment of infections and also highlight the need for regular reporting and antibiogram guided antibiotic prescription.

Bangladesh Med Res Counc Bull 2021; 47(2): 181-187

Downloads

Download data is not yet available.
Abstract
173
PDF
119

Downloads

Published

2022-05-17

How to Cite

Jobayer, M., Rahman, M., Akter, N., Shareef, N., Rana, R. A., & Shamsuzzaman, S. (2022). Organisms isolated from wound swab and pus with their antibiotic susceptibility pattern in a tertiary care hospital in Bangladesh.: Antibiogram of organisms from wound infection. Bangladesh Medical Research Council Bulletin, 47(2), 181–187. https://doi.org/10.3329/bmrcb.v47i2.57777

Issue

Vol. 47 No. 2 (2021)

Section

Research Papers

License

Copyright (c) 2021 Mohammad Jobayer, Mizanur Rahman, Nadira Akter, Naomee Shareef, Rubina Afroz Rana, SM Shamsuzzaman

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms.

Authors retain copyright and grant the journal right of first publication.

Creative Commons Licence
Articles in the Bangladesh Medical Research Council Bulletin are licensed under a Creative Commons Attribution 4.0 International License (CC-BY) that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).