Assessment of Vitamin D Status and Response to Vitamin D Supplementation in Obese and Non-obese Children at a Tertiary Care Hospital

Vitamin D Status in Obese and Non-obese Children

Authors

  • Suraiya Begum Department of Paediatrics, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
  • Farzana Sharmin Department of Paediatrics, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
  • Kohinoor Jahan Shayamaly Department of Paediatrics, District Hospital, Sherpur, Dhaka, Bangladesh.
  • Dhiraj Chandra Biswas Department of Paediatrics, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
  • Anika Tasneem Chowdhury Project Research Physician, International Center for Diarrhoeal Diseases Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
  • Shohely Parveen Department of Paediatrics, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
  • Tanjida Chowdhury Department of Paediatrics, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.

DOI:

https://doi.org/10.3329/bmrcb.v48i2.62292

Keywords:

Vitamin D, Overweight, obese, non-obese, vitamin D deficiency

Abstract

Background: Obesity seems to be a critical issue nowadays because of its high prevalence and its adverse effects on health. There is some evidence indicating the relationship between obesity and lower serum 25- hydroxyvitamin D concentration. Objectives: The objectives of this study were to assess the vitamin D status and estimate the response to vitamin D in obese and non-obese children after vitamin D supplementation.

Methods: This was a Quasi experimental study, done in Paediatric Endocrinology Clinic and Paediatric Outdoor, Bangabandhu Shiekh Mujib Medical University (BSMMU) from August 2018 to February 2019. Vitamin D was measured in 20 obese and 20 non-obese children aged 10-18 years. Hypovitaminosis D was observed in all (100%) obese children and 15 (75%) non-obese children. Four thousand IU was given orally daily in obese and non-obese vitamin D deficient children for 3 months. Serum levels of vitamin D, calcium, inorganic phosphate, Alkaline Phosphatase (ALP) and Parathormone (PTH) also measured before and after vitamin D supplementation.

Results: The mean age was 11.64±1.40 years in obese and11.15±2.40 years in non-obese children, and male female ratio was 1:1.3. Hypovitaminosis D was present in 100% in obese and 75% in non-obese children. Vitamin D deficiency (VDD) was observed in 85% and vitamin D insufficiency (VDI) was in 15% in obese children. In non-obese children VDD was observed in 86.7% and VDI in 13.3% cases. In both the groups serum vitamin D was increased, alkaline phosphatase and parathormone levels were decreased significantly, and serum calcium was increased and serum inorganic phosphatase was decreased but not statistically significant after four thousand IU daily vitamin D supplementation for three months. After vitamin D supplementation, vitamin D status were found normal in 60% obese and 53.3% non-obese children, VDI were in 30% obese/overweight and 26.7% in non-obese children, and VDD were in 10% obese/overweight and 20% in non-obese children.

Conclusion: VDD was observed in both obese and non-obese children. Therapeutic responses were observed with 4000 IU/day vitamin D supplementation for three months in both the groups.

Bangladesh Medical Res Counc Bull 2022; 48: 90-96

Downloads

Download data is not yet available.
Abstract
34
PDF
49

Downloads

Published

2023-05-28

How to Cite

Begum, S., Sharmin, F., Shayamaly, K. J., Biswas, D. C., Chowdhury, A. T., Parveen, S., & Chowdhury, T. (2023). Assessment of Vitamin D Status and Response to Vitamin D Supplementation in Obese and Non-obese Children at a Tertiary Care Hospital: Vitamin D Status in Obese and Non-obese Children. Bangladesh Medical Research Council Bulletin, 48(2), 90–96. https://doi.org/10.3329/bmrcb.v48i2.62292

Issue

Vol. 48 No. 2 (2022)

Section

Research Papers

License

Copyright (c) 2022 Suraiya Begum, Farzana Sharmin, Kohinoor Jahan Shayamaly, Dhiraj Chandra Biswas, Anika Tasneem Chowdhury, Shohely Parveen, Tanjida Chowdhury

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms.

Authors retain copyright and grant the journal right of first publication.

Creative Commons Licence
Articles in the Bangladesh Medical Research Council Bulletin are licensed under a Creative Commons Attribution 4.0 International License (CC-BY) that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).