Correlation of Pap Smear and Colposcopy in Relation to Histopathological Findings in Detection of Preinvasive Lesion of Cervix in Bangabandhu Sheikh Mujib Medical University Hospital Dhaka Bangladesh

Authors

  • Noor-e- Ferdous Department of Gynecological Oncology BSMMU, Shahbag, Dhaka, Bangladesh.
  • Shirin Akter Begum Department of Gynecological Oncology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh
  • Mehriban Amatullah Department of Obstetrics and Gynaecology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh
  • Shereen Yousuf Department of Obstetrics and Gynaecology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh
  • Tasfia Mahmud Sirajul Islam Medical College, Dhaka, Bangladesh
  • Latifa Akhter Department of Gynecological Oncology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh
  • Farzana Sharmin Department of Gynecological Oncology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh
  • Khairun Nahar Department of Obstetrics and Gynaecology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh
  • Afroza Khanom Department of Gynaecological Oncology, National Institute of Cancer Research & Hospital (NICRH), Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/bmrcb.v48i3.63810

Keywords:

Pap smear, Colposcopy, precancerous lesions, histopathology, HSIL, LSIL

Abstract

Background: Cervical cancer develops from well-defined precursor lesions in a variable period of time. Detecting in early or pre invasive stages, cervical cancer is preventable and curable, so detection of preinvasive lesions is very important.

Objectives: The aim of our study was to correlate of Pap smear and colposcopy in relation to histopathological findings in detection of preinvasive lesion of cervix.

Methods: This was a cross-sectional study of 110 women to attend in department of Gynecological Oncology OPD of Bangabandhu Sheikh Mujib Medical University Hospital from July 2016 to June 2017. Inclusion criteria were age of 30 to 60 years, who had unhealthy cervix, intermenstrual or post coital bleeding and excessive vaginal discharge. Exclusion criteria were any cervical growth, bleeding at the time of examination, pregnant women.

Result: In present study sensitivity of Pap smear for detecting lesions above LSIL was 11(10.0%), specificity 68.38%, PPV was 94.44%, negative predictive value 71.86%. The incidence of preinvasive lesions (LSIL and HSIL) was 33.64% with LSIL 21(19.09%) and HSIL 16(14.55%) and of carcinoma were 10(9.09%).

Conclusion: With a comprehensive approach to make awareness and doing proper screening by Paps smear, colposcopy and colposcopy directed biopsy; cervical cancer can be eliminated as a public health problem within a generation.

Bangladesh Medical Res Counc Bull 2022; 48(3): 189-194

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Published

2023-05-30

How to Cite

Ferdous, N.- e-., Begum, S. A. ., Amatullah, M., Yousuf, S. ., Mahmud, T., Akhter, L. ., Sharmin, F., Nahar, K. ., & Khanom, A. (2023). Correlation of Pap Smear and Colposcopy in Relation to Histopathological Findings in Detection of Preinvasive Lesion of Cervix in Bangabandhu Sheikh Mujib Medical University Hospital Dhaka Bangladesh. Bangladesh Medical Research Council Bulletin, 48(3), 189–194. https://doi.org/10.3329/bmrcb.v48i3.63810

Issue

Vol. 48 No. 3 (2022)

Section

Research Papers

License

Copyright (c) 2022 Noor-e- Ferdous, Shirin Akter Begum, Mehriban Amatullah, Shereen Yousuf, Tasfia Mahmud, Latifa Akhter, Farzana Sharmin, Khairun Nahar, Afroza Khanom

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