Comparative Study of Antidiabetic Activity of Hexane-Extract of Lemon Peel (Limon citrus) and Glimepiride in Alloxan-Induced Diabetic Rats

Authors

  • Mohammad Naim Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka
  • Farhad Mohammad Amjad Dhaka Medical College, Dhaka
  • Sania Sultana Dhaka Medical College, Dhaka
  • Sheikh Nazrul Islam Institute of Nutrition and Food Sciences, Dhaka University, Dhaka
  • Muhammad Amjad Hossain Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka,
  • Rehana Begum Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka,
  • Mohammad Abdur Rashid Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka,
  • Mohammad Shah Amran Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka,

DOI:

https://doi.org/10.3329/bpj.v15i2.12577

Keywords:

Diabetic, Alloxan, glimepiride, lemon peel, glucometer

Abstract

Diabetes is classified as a metabolic disorder manifested by elevated level of glucose in the blood. An attempt has been made to compare the antidiabetic activity of hexane extract of lemon peel (Citrus Limon) with that of a marketed product, glimepiride, in alloxan-induced diabetic rats. The study was performed by the measurement of blood glucose level using a glucometer. It was found that the hexane extract of lemon peel showed antidiabetic activity comparable to that of glimepiride. It can thus be inferred that the extract of lemon peel possesses significant antidiabetic activity.

DOI: http://dx.doi.org/10.3329/bpj.v15i2.12577

Bangladesh Pharmaceutical Journal 15(2): 131-134, 2012

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Published

2012-11-12

How to Cite

Naim, M., Amjad, F. M., Sultana, S., Islam, S. N., Hossain, M. A., Begum, R., Rashid, M. A., & Amran, M. S. (2012). Comparative Study of Antidiabetic Activity of Hexane-Extract of Lemon Peel (Limon citrus) and Glimepiride in Alloxan-Induced Diabetic Rats. Bangladesh Pharmaceutical Journal, 15(2), 131–134. https://doi.org/10.3329/bpj.v15i2.12577

Issue

Vol. 15 No. 2 (2012)

Section

Articles