Membrane Stabilizing and Thrombolytic Activities of Sida rhombifolia L.

Authors

  • Mohammd Firoz Khan Department of Pharmacy, State University of Bangladesh, Dhaka- 1205
  • Sikder Nahidul Islam Rabbi Department of Pharmacy, State University of Bangladesh, Dhaka- 1205
  • Md Aslam Hossain Department of Pharmaceutical Chemistry, University of Dhaka, Dhaka- 1000
  • Mohammad A Rashid Department of Pharmaceutical Chemistry, University of Dhaka, Dhaka- 1000

DOI:

https://doi.org/10.3329/bpj.v17i1.22313

Keywords:

Sida rhombifolia, membrane stabilization, thrombolysis

Abstract

The crude methanol extract of whole plant of Sida rhombifolia and different fractions generated from it were tested for membrane stabilizing and thrombolytic activities. In hypotonic solution- and heat-induced conditions, the chloroform soluble partitionates inhibited haemolysis of human erythrocyte by 22.11±0.14% and 64.71±0.08%, respectively as compared to 71.97±0.51% and 40.12±0.29% demonstrated by the standard acetyl salicylic acid (ASA). Moreover, the pet ether soluble materials revealed highest thrombolytic activity with clot lysis value of 19.51±0.03% as compared to 66.98±0.11% exhibited by the standard streptokinase.

DOI: http://dx.doi.org/10.3329/bpj.v17i1.22313

Bangladesh Pharmaceutical Journal 17(1): 43-45, 2014

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Published

2015-02-21

How to Cite

Khan, M. F., Rabbi, S. N. I., Hossain, M. A., & Rashid, M. A. (2015). Membrane Stabilizing and Thrombolytic Activities of Sida rhombifolia L. Bangladesh Pharmaceutical Journal, 17(1), 43–45. https://doi.org/10.3329/bpj.v17i1.22313

Issue

Vol. 17 No. 1 (2014)

Section

Articles