Synthesis, Characterization and Antibacterial Studies of the Mixed Ligand Complexes of Pd(II) and Pt(II) Ions with Phthalic Acid and Heterocyclic Amines

Authors

  • Md Belayet Hossain Department of Chemistry, Khulna University of Engineering & Technology, Khulna-9203
  • Md Abdus Salam Department of Chemistry, University of Dhaka, Dhaka-1000
  • Abdur Rashed Fish Inspection & Quality Control, DoF, Khulna-9000
  • MA Yousuf Department of Chemistry, Khulna University of Engineering & Technology, Khulna-9203

DOI:

https://doi.org/10.3329/bpj.v17i2.22333

Keywords:

Mixed ligand complex, phthalate, 2-aminopyridine, 4-picoline, anti-bacterial

Abstract

Mixed ligand complexes of Pd(II) and Pt(II) ions with phthalic acid and heterocyclic amines were synthesized and characterized. The general formula of the complexes is [MLL/]; where, M = Pd(II)(1-2), Pt(II)(3); L = phthalate, C8H4O4, L/ = pyridine, C5H5N(1); 2-aminopyridine, C5H6N2(2) and 4-picoline, C6H7N(3). The complexes were synthesized in the solid form and characterized by elemental analysis, electrical conductivity, magnetic measurements, and spectroscopic studies. Spectral analyses and magnetic measurements revealed the coordination of metal ion with ligands and geometry of the complexes. Anti-bacterial activity of the complexes against seven pathogenic bacteria (three gram positive and four gram negative) was assessed by the disc diffusion method. Complexes [Pd(Ph)(2-apy)] and [Pt(Ph)(4-pico)2] showed the highest anti-bacterial activity (when, Ph = bidentate phthalate, 2-apy = 2-aminopyridine and 4-pico = 4-picoline).

DOI: http://dx.doi.org/10.3329/bpj.v17i2.22333

Bangladesh Pharmaceutical Journal 17(2): 157-162, 2014

Downloads

Download data is not yet available.
Abstract
833
PDF
1170

Downloads

Published

2015-02-21

How to Cite

Hossain, M. B., Salam, M. A., Rashed, A., & Yousuf, M. (2015). Synthesis, Characterization and Antibacterial Studies of the Mixed Ligand Complexes of Pd(II) and Pt(II) Ions with Phthalic Acid and Heterocyclic Amines. Bangladesh Pharmaceutical Journal, 17(2), 157–162. https://doi.org/10.3329/bpj.v17i2.22333

Issue

Section

Articles