Comparative studies of hydration behaviour and density of Pyrrolidone K-30, PEG 6000 and PEG 20000

Authors

  • Sakina Sultana Department of Pharmacy, Jahangirnagar University, Savar, Dhaka-1342
  • Md Ohidullah Department of Pharmacy, Jahangirnagar University, Savar, Dhaka-1342
  • AHM Saifuddin Department of Pharmacy, Jahangirnagar University, Savar, Dhaka-1342
  • Md Saddam Hossain Department of Pharmacy, Jahangirnagar University, Savar, Dhaka-1342

DOI:

https://doi.org/10.3329/bpj.v18i1.23515

Keywords:

Pyrrolidone K-30, PEGs, Hydration and Density

Abstract

A comparative study was conducted on aqueous solutions of Pyrrolidone K-30 and Polyethylene glycols of molecular weight 6000 and 20000, respectively for investigating their hydration behaviour in terms of intrinsic viscosity and density. In the study, Pyrrolidone K-30 exhibited the intrinsic viscosity of ~14 g/ml, while PEG 6000 and PEG 20000 revealed the intrinsic viscosities of 18 g/ml and 28 g/ml, respectively at a room temperature of 298 ± 1º K. Thus, among these three compounds PEG 20000 exhibited the highest intrinsic viscosity which was interesting. In density measurement this compound showed a non-linear trend of change in density as concentration was varied. Such results were opposite to that observed with the remaining two compounds.

Bangladesh Pharmaceutical Journal 18(1): 48-52, 2015

Downloads

Download data is not yet available.
Abstract
926
PDF
1266

Author Biography

Sakina Sultana, Department of Pharmacy, Jahangirnagar University, Savar, Dhaka-1342



Downloads

Published

2015-06-01

How to Cite

Sultana, S., Ohidullah, M., Saifuddin, A., & Hossain, M. S. (2015). Comparative studies of hydration behaviour and density of Pyrrolidone K-30, PEG 6000 and PEG 20000. Bangladesh Pharmaceutical Journal, 18(1), 48–52. https://doi.org/10.3329/bpj.v18i1.23515

Issue

Section

Articles