Exploration of antibacterial metabolites producing marine bacteria from Sundarbans, Bangladesh

Authors

  • Ashish Kumar Sarker Department of Pharmacy, Pabna University of Science and Technology, Pabna-6600
  • Md Anwarul Haque Department of Pharmacy, Pabna University of Science and Technology, Pabna-6600
  • Mohammad Sayful Islam Department of Pharmacy, University of Rajshahi, Rajshahi-6205
  • Md Ajijur Rahman Department of Pharmacy, University of Rajshahi, Rajshahi-6205
  • Md Anwar Ul Islam Department of Pharmacy, University of Rajshahi, Rajshahi-6205

DOI:

https://doi.org/10.3329/bpj.v18i1.23516

Keywords:

Marine bacteria, Antibacterial, Secondary metabolites, Isolation, Sundarbans

Abstract

To combat the increasing numbers of antibiotic resistant strains of pathogenic bacteria new source of antibacterial agents are desperately needed. This study was aimed to discover new marine bacteria having antibacterial activity from marine soil samples of Sundarbans, Bangladesh. Using starch-casein-nitrate-agar medium thirty nine marine bacteria colonies were isolated as pure isolates from nine marine soil samples. Each of the isolates was preserved in both short term and long term basis. Based on the aerial and substrate mycelia color of the isolates they were grouped into five color series and were screened for their antibacterial activity against a series of test bacteria. Among thirty nine pure isolates twenty four isolates (61.5%) exhibited moderate to high activity against three grampositive and four gram-negative bacteria. This is due to the antibacterial metabolites secreted in the medium by most of the isolates. It suggested that Sundarbans may be an interesting, valuable and potential source for the exploration of novel marine bacteria with the potential to yield useful new antibacterial secondary metabolites of pharmaceutical interest.

Bangladesh Pharmaceutical Journal 18(1): 53-60, 2015

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Published

2015-06-01

How to Cite

Sarker, A. K., Haque, M. A., Islam, M. S., Rahman, M. A., & Islam, M. A. U. (2015). Exploration of antibacterial metabolites producing marine bacteria from Sundarbans, Bangladesh. Bangladesh Pharmaceutical Journal, 18(1), 53–60. https://doi.org/10.3329/bpj.v18i1.23516

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Articles