Chemical Modification of Chitosan in order to Inverse Swelling Behavior: Comparison between Crosslinking, Michael Addition and Graft Copolymerization Reactions

Authors

  • Solmaz Zakhireh Department of Chemistry, Tabriz Branch, Islamic Azad University, Tabriz
  • Mehrdad Mahkam Chemistry Department, Faculty of Science, Azarbaijan Shahid Madani University, Tabriz
  • Yousef Toomari Laboratory of Dendrimers and Nanobiopolymers, Faculty of Chemistry, University of Tabriz, Tabriz
  • Saeed Jafarirad Research Institute for Fundamental Sciences (RIFS), University of Tabriz, Tabriz

DOI:

https://doi.org/10.3329/bpj.v18i2.24307

Keywords:

Chitosan, Cross-linking, Michael addition, Graft copolymerization, Swelling

Abstract

In the present work, three methods were used to inverse chitosan swelling behavior including, conjugation of p-amino benzoic acid (PABA) on cross-linked chitosan in different condition, Michael addition reaction of acrylic acid (AA) on chitosan and finally graft copolymerization of methacrylic acid (MMA) on chitosan. We couldnt inverse chitosan swelling behavior by the Michael addition reaction of acrylic acid, but conjugation of PABA on cross-linked chitosan inversed the chitosan swelling behavior. In addition, the graft copolymerization of MMA on chitosan was also successful. In general, the third method, among the above-mentioned modifications provided the best results.

Bangladesh Pharmaceutical Journal 18(2): 110-117, 2015

Downloads

Download data is not yet available.
Abstract
191
PDF
178

Author Biography

Solmaz Zakhireh, Department of Chemistry, Tabriz Branch, Islamic Azad University, Tabriz



Downloads

Published

2015-07-26

How to Cite

Zakhireh, S., Mahkam, M., Toomari, Y., & Jafarirad, S. (2015). Chemical Modification of Chitosan in order to Inverse Swelling Behavior: Comparison between Crosslinking, Michael Addition and Graft Copolymerization Reactions. Bangladesh Pharmaceutical Journal, 18(2), 110–117. https://doi.org/10.3329/bpj.v18i2.24307

Issue

Section

Articles