Boehmeria glomerulifera Miq. Exhibits in vivo Antidepressant and Antidiarrheal Activities

Authors

  • Muhammed Mahfuzur Rahman Department of Pharmacy, State University of Bangladesh, Dhaka-1205, Bangladesh
  • Sharmin Khandker Shampa Department of Pharmacy, State University of Bangladesh, Dhaka-1205, Bangladesh
  • Md Abdul Bari Department of Pharmacy, State University of Bangladesh, Dhaka-1205, Bangladesh
  • Mohammad Kaisarul Islam Phytochemical Research Laboratory, Department of Pharmaceutical Chemistry University of Dhaka, Dhaka-1000, Bangladesh
  • Mohammad A Rashid

DOI:

https://doi.org/10.3329/bpj.v22i2.42302

Keywords:

Boehmeria glomerulifera, cytotoxic, sedative, anti-diarrheal

Abstract

Boehmeria glomerulifera Miq., is medicinal herb belongs to the family Urticaceae. It is used for treating various diseases by folk practitioners and rural people. The CNS antidepressant and antidiarrhoeal activities of the crude extract were investigated at 200 and 400 mg/kg bw in Swiss Albino mice model. The crude methanolic extract revealed significant (p < 0.05) antidepressant activity in mice at 400 mg/kg bw. On the other hand, in the castor oil-induced antidiarrheal assay, the extract demonstrated significant (p < 0.05) antidiarrhoeal activity at 400 mg/kg bw.

Bangladesh Pharmaceutical Journal 22(2): 181-184, 2019

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Published

2019-07-21

How to Cite

Rahman, M. M., Shampa, S. K., Bari, M. A., Islam, M. K., & Rashid, M. A. (2019). Boehmeria glomerulifera Miq. Exhibits in vivo Antidepressant and Antidiarrheal Activities. Bangladesh Pharmaceutical Journal, 22(2), 181–184. https://doi.org/10.3329/bpj.v22i2.42302

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Articles